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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED27 All Species: 30.61
Human Site: S27 Identified Species: 61.21
UniProt: Q6P2C8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P2C8 NP_004260.2 311 35432 S27 A I Q A L R S S V S R V F D C
Chimpanzee Pan troglodytes XP_526874 311 35434 S27 A I Q A L H S S G S R V F D C
Rhesus Macaque Macaca mulatta XP_001105126 311 35440 S27 A I Q A L R S S V S R V F D C
Dog Lupus familis XP_849826 311 35341 S27 A I Q A L R S S V S R V F D C
Cat Felis silvestris
Mouse Mus musculus Q9DB40 311 35279 S27 A I Q A L R S S V S R V F D C
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506492 243 27824
Chicken Gallus gallus XP_415455 312 35236 S28 A I Q A L R S S V T R V F D C
Frog Xenopus laevis Q3B8G8 311 35405 S27 C I Q A L R S S V T R V F D C
Zebra Danio Brachydanio rerio Q6PFL0 311 35653 S27 A I Q A L R S S V T R V F D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNG0 293 33850 L20 N L R S N V R L C F E H L A D
Honey Bee Apis mellifera XP_396939 298 33938 G25 K V L R S S V G Q V F D S L G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780142 244 27952
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 99.6 98 N.A. 98 N.A. N.A. 77.4 94.2 89.3 88.4 N.A. 38.9 39.5 N.A. 36.3
Protein Similarity: 100 97.1 100 99.6 N.A. 99.6 N.A. N.A. 77.8 97.7 93.8 93.5 N.A. 60.7 61.7 N.A. 54
P-Site Identity: 100 86.6 100 100 N.A. 100 N.A. N.A. 0 93.3 86.6 86.6 N.A. 0 0 N.A. 0
P-Site Similarity: 100 86.6 100 100 N.A. 100 N.A. N.A. 0 100 93.3 93.3 N.A. 20 6.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 59 0 0 67 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 59 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 0 67 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 9 0 67 0 9 % F
% Gly: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 9 0 67 0 0 9 0 0 0 0 9 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 67 0 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 9 9 0 59 9 0 0 0 67 0 0 0 0 % R
% Ser: 0 0 0 9 9 9 67 67 0 42 0 0 9 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 % T
% Val: 0 9 0 0 0 9 9 0 59 9 0 67 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _