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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED27 All Species: 33.33
Human Site: S81 Identified Species: 66.67
UniProt: Q6P2C8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P2C8 NP_004260.2 311 35432 S81 S N L V G K P S E N H P L H N
Chimpanzee Pan troglodytes XP_526874 311 35434 S81 R N L V G K P S E N H P L H N
Rhesus Macaque Macaca mulatta XP_001105126 311 35440 S81 S N L V G K P S E N H P L H N
Dog Lupus familis XP_849826 311 35341 S81 S N L V G K P S E N H P L H N
Cat Felis silvestris
Mouse Mus musculus Q9DB40 311 35279 S81 S N L V G K P S E N H P L H N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506492 243 27824 S21 E N H P L H N S G L L S L D P
Chicken Gallus gallus XP_415455 312 35236 S82 S N L V G K P S E N H P L H N
Frog Xenopus laevis Q3B8G8 311 35405 S81 S N L V G K P S E N L P L H N
Zebra Danio Brachydanio rerio Q6PFL0 311 35653 S81 S T L V G R P S E S H P L H N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNG0 293 33850 T71 N G L P V P P T P Y S L G N T
Honey Bee Apis mellifera XP_396939 298 33938 P76 A V S S L N P P P G A F H L A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780142 244 27952 I22 R Q R E A E T I G N T G A L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 99.6 98 N.A. 98 N.A. N.A. 77.4 94.2 89.3 88.4 N.A. 38.9 39.5 N.A. 36.3
Protein Similarity: 100 97.1 100 99.6 N.A. 99.6 N.A. N.A. 77.8 97.7 93.8 93.5 N.A. 60.7 61.7 N.A. 54
P-Site Identity: 100 93.3 100 100 N.A. 100 N.A. N.A. 20 100 93.3 80 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 93.3 100 100 N.A. 100 N.A. N.A. 20 100 93.3 93.3 N.A. 33.3 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 0 0 0 0 9 0 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 9 0 0 9 0 9 0 0 67 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 9 0 0 67 0 0 0 17 9 0 9 9 0 0 % G
% His: 0 0 9 0 0 9 0 0 0 0 59 0 9 67 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 75 0 17 0 0 0 0 9 17 9 75 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 67 0 0 0 9 9 0 0 67 0 0 0 9 67 % N
% Pro: 0 0 0 17 0 9 84 9 17 0 0 67 0 0 9 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 17 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 59 0 9 9 0 0 0 75 0 9 9 9 0 0 9 % S
% Thr: 0 9 0 0 0 0 9 9 0 0 9 0 0 0 9 % T
% Val: 0 9 0 67 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _