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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED27
All Species:
31.21
Human Site:
T223
Identified Species:
62.42
UniProt:
Q6P2C8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2C8
NP_004260.2
311
35432
T223
G
Y
N
E
N
V
Y
T
E
D
G
K
L
D
I
Chimpanzee
Pan troglodytes
XP_526874
311
35434
T223
G
Y
N
E
N
V
Y
T
E
D
G
K
L
D
I
Rhesus Macaque
Macaca mulatta
XP_001105126
311
35440
T223
G
Y
N
E
N
V
Y
T
E
D
G
K
L
D
I
Dog
Lupus familis
XP_849826
311
35341
T223
G
Y
S
E
N
V
Y
T
E
D
G
K
L
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB40
311
35279
T223
G
Y
N
E
S
V
Y
T
E
D
G
K
L
D
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506492
243
27824
W163
E
D
G
K
L
D
I
W
S
K
S
N
Y
Q
V
Chicken
Gallus gallus
XP_415455
312
35236
T224
G
Y
N
E
N
V
Y
T
D
D
G
K
L
D
I
Frog
Xenopus laevis
Q3B8G8
311
35405
T223
G
Y
T
E
N
V
Y
T
E
D
G
K
L
D
I
Zebra Danio
Brachydanio rerio
Q6PFL0
311
35653
T223
G
F
H
E
N
I
Y
T
E
D
R
K
L
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNG0
293
33850
A213
L
E
H
D
D
L
W
A
E
S
R
Y
E
V
F
Honey Bee
Apis mellifera
XP_396939
298
33938
W218
Y
G
E
T
M
D
L
W
T
E
S
R
H
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780142
244
27952
W164
D
D
G
T
L
D
L
W
T
A
S
K
Y
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
99.6
98
N.A.
98
N.A.
N.A.
77.4
94.2
89.3
88.4
N.A.
38.9
39.5
N.A.
36.3
Protein Similarity:
100
97.1
100
99.6
N.A.
99.6
N.A.
N.A.
77.8
97.7
93.8
93.5
N.A.
60.7
61.7
N.A.
54
P-Site Identity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
0
93.3
93.3
73.3
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
13.3
100
93.3
93.3
N.A.
40
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
17
0
9
9
25
0
0
9
67
0
0
0
67
0
% D
% Glu:
9
9
9
67
0
0
0
0
67
9
0
0
9
9
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
67
9
17
0
0
0
0
0
0
0
59
0
0
0
0
% G
% His:
0
0
17
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
67
% I
% Lys:
0
0
0
9
0
0
0
0
0
9
0
75
0
9
0
% K
% Leu:
9
0
0
0
17
9
17
0
0
0
0
0
67
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
42
0
59
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
17
9
0
0
0
% R
% Ser:
0
0
9
0
9
0
0
0
9
9
25
0
0
0
0
% S
% Thr:
0
0
9
17
0
0
0
67
17
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
59
0
0
0
0
0
0
0
9
25
% V
% Trp:
0
0
0
0
0
0
9
25
0
0
0
0
0
0
0
% W
% Tyr:
9
59
0
0
0
0
67
0
0
0
0
9
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _