KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDC4
All Species:
25.15
Human Site:
S1058
Identified Species:
55.33
UniProt:
Q6P2E9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2E9
NP_055144.3
1401
151661
S1058
V
P
P
C
V
S
R
S
L
E
P
M
A
G
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089684
1300
138998
A976
M
Q
A
M
R
S
A
A
G
T
P
V
P
S
A
Dog
Lupus familis
XP_546871
1484
160920
S1141
V
P
P
C
V
S
R
S
L
E
P
V
A
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3UJB9
1406
152465
S1063
V
P
P
C
V
S
R
S
L
E
P
V
A
G
Q
Rat
Rattus norvegicus
Q3ZAV8
1407
152577
S1064
V
P
P
C
V
S
R
S
L
E
P
V
A
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414022
1419
155974
S1076
V
P
Q
C
I
S
K
S
V
D
P
V
A
G
Q
Frog
Xenopus laevis
Q7ZXT3
1391
153901
T1048
V
S
Q
C
I
S
K
T
L
D
P
V
A
A
Q
Zebra Danio
Brachydanio rerio
Q1LUT1
1384
151831
S1044
V
P
Q
T
I
S
K
S
L
E
P
V
T
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKK1
1354
149232
N1028
L
L
P
R
V
N
A
N
M
D
Q
L
Q
A
Q
Honey Bee
Apis mellifera
XP_396550
1075
119372
E759
T
T
L
P
R
I
I
E
D
T
V
E
P
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784386
1287
142473
V962
T
S
R
L
D
K
T
V
R
L
E
I
E
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
63.8
90.1
N.A.
94.8
94.4
N.A.
N.A.
74.3
62.4
61.6
N.A.
25.1
29.9
N.A.
32.9
Protein Similarity:
100
N.A.
70.2
91.5
N.A.
97
96.8
N.A.
N.A.
84.9
78.5
77.4
N.A.
45.4
48.1
N.A.
50.6
P-Site Identity:
100
N.A.
13.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
60
46.6
60
N.A.
20
0
N.A.
0
P-Site Similarity:
100
N.A.
33.3
100
N.A.
100
100
N.A.
N.A.
93.3
80
80
N.A.
60
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
19
10
0
0
0
0
55
19
10
% A
% Cys:
0
0
0
55
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
28
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
46
10
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
55
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
28
10
10
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
10
28
0
0
0
0
0
0
0
19
% K
% Leu:
10
10
10
10
0
0
0
0
55
10
0
10
0
10
0
% L
% Met:
10
0
0
10
0
0
0
0
10
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
55
46
10
0
0
0
0
0
0
73
0
19
0
0
% P
% Gln:
0
10
28
0
0
0
0
0
0
0
10
0
10
0
73
% Q
% Arg:
0
0
10
10
19
0
37
0
10
0
0
0
0
0
0
% R
% Ser:
0
19
0
0
0
73
0
55
0
0
0
0
0
19
0
% S
% Thr:
19
10
0
10
0
0
10
10
0
19
0
0
10
0
0
% T
% Val:
64
0
0
0
46
0
0
10
10
0
10
64
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _