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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM53
All Species:
13.94
Human Site:
S208
Identified Species:
25.56
UniProt:
Q6P2H8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2H8
NP_078863.2
277
31630
S208
D
R
L
Q
D
A
G
S
R
W
P
E
L
Y
L
Chimpanzee
Pan troglodytes
XP_513099
204
23435
A152
R
A
D
E
V
V
L
A
R
D
I
E
R
M
V
Rhesus Macaque
Macaca mulatta
XP_001093396
204
23354
A152
R
A
D
E
V
V
P
A
R
D
V
E
R
M
V
Dog
Lupus familis
XP_539639
278
31512
S209
D
R
L
L
D
A
A
S
R
W
P
E
L
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0Z3
276
31570
S207
D
R
L
Q
D
S
G
S
C
W
P
E
L
Y
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJC8
285
32654
S202
D
A
M
K
K
D
S
S
R
W
P
Q
L
Y
L
Zebra Danio
Brachydanio rerio
Q6DHN0
281
32493
A202
D
A
M
M
E
H
P
A
P
W
P
Q
M
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610178
343
39125
N251
C
D
L
K
N
E
A
N
R
Y
P
Q
L
F
L
Honey Bee
Apis mellifera
XP_392954
326
37186
Y216
I
G
L
A
E
E
S
Y
S
W
P
Q
L
F
L
Nematode Worm
Caenorhab. elegans
NP_491980
325
37453
L254
Y
L
Q
T
H
I
A
L
P
R
D
Q
L
Y
L
Sea Urchin
Strong. purpuratus
XP_788598
287
32857
M216
R
A
M
L
A
D
K
M
Q
C
P
Q
L
F
L
Poplar Tree
Populus trichocarpa
XP_002306371
443
48844
P369
S
L
L
S
S
G
Q
P
S
C
P
Q
L
Y
I
Maize
Zea mays
NP_001146062
309
34480
P231
E
L
L
S
W
K
Q
P
K
C
P
Q
L
Y
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.2
71.8
88.8
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
54
48
N.A.
30.8
30.3
24
33.1
Protein Similarity:
100
73.2
72.5
92.8
N.A.
91.6
N.A.
N.A.
N.A.
N.A.
68.4
65.1
N.A.
48.9
48.4
42.1
51.9
P-Site Identity:
100
13.3
13.3
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
53.3
33.3
N.A.
33.3
33.3
20
20
P-Site Similarity:
100
33.3
33.3
86.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
73.3
66.6
N.A.
73.3
53.3
26.6
46.6
Percent
Protein Identity:
22.3
26.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
36.1
46.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
53.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
0
8
8
16
24
24
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
8
24
0
0
0
0
0
% C
% Asp:
39
8
16
0
24
16
0
0
0
16
8
0
0
0
0
% D
% Glu:
8
0
0
16
16
16
0
0
0
0
0
39
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
0
% F
% Gly:
0
8
0
0
0
8
16
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
16
% I
% Lys:
0
0
0
16
8
8
8
0
8
0
0
0
0
0
0
% K
% Leu:
0
24
54
16
0
0
8
8
0
0
0
0
77
0
70
% L
% Met:
0
0
24
8
0
0
0
8
0
0
0
0
8
16
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
16
16
16
0
77
0
0
0
0
% P
% Gln:
0
0
8
16
0
0
16
0
8
0
0
62
0
0
0
% Q
% Arg:
24
24
0
0
0
0
0
0
47
8
0
0
16
0
0
% R
% Ser:
8
0
0
16
8
8
16
31
16
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
16
16
0
0
0
0
8
0
0
0
16
% V
% Trp:
0
0
0
0
8
0
0
0
0
47
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
8
0
0
0
62
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _