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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM53
All Species:
16.06
Human Site:
S254
Identified Species:
29.44
UniProt:
Q6P2H8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2H8
NP_078863.2
277
31630
S254
F
V
S
S
A
H
V
S
H
L
R
D
Y
P
T
Chimpanzee
Pan troglodytes
XP_513099
204
23435
Y186
H
V
S
H
L
R
D
Y
P
T
Y
Y
T
S
L
Rhesus Macaque
Macaca mulatta
XP_001093396
204
23354
Y186
H
V
S
H
L
R
D
Y
P
T
Y
Y
T
S
L
Dog
Lupus familis
XP_539639
278
31512
S255
F
V
S
S
A
H
V
S
H
L
R
D
Y
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0Z3
276
31570
S253
F
V
S
S
A
H
V
S
H
L
R
D
Y
P
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJC8
285
32654
S248
F
G
K
S
E
H
V
S
H
F
R
R
F
P
H
Zebra Danio
Brachydanio rerio
Q6DHN0
281
32493
S248
F
I
T
P
A
H
V
S
L
F
R
D
C
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610178
343
39125
K297
F
E
D
A
E
H
V
K
I
Y
T
K
Y
P
K
Honey Bee
Apis mellifera
XP_392954
326
37186
K262
F
T
N
S
P
H
V
K
H
Y
A
T
Y
R
D
Nematode Worm
Caenorhab. elegans
NP_491980
325
37453
A300
F
V
D
S
E
H
V
A
H
I
R
T
H
P
K
Sea Urchin
Strong. purpuratus
XP_788598
287
32857
A262
W
E
D
S
D
H
V
A
H
L
R
K
H
P
E
Poplar Tree
Populus trichocarpa
XP_002306371
443
48844
D415
F
V
F
T
P
H
V
D
H
F
R
N
D
P
K
Maize
Zea mays
NP_001146062
309
34480
D277
F
V
S
S
P
H
V
D
H
Y
R
S
N
P
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.2
71.8
88.8
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
54
48
N.A.
30.8
30.3
24
33.1
Protein Similarity:
100
73.2
72.5
92.8
N.A.
91.6
N.A.
N.A.
N.A.
N.A.
68.4
65.1
N.A.
48.9
48.4
42.1
51.9
P-Site Identity:
100
13.3
13.3
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
53.3
53.3
N.A.
33.3
40
53.3
46.6
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
60
66.6
N.A.
40
46.6
73.3
66.6
Percent
Protein Identity:
22.3
26.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
36.1
46.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
46.6
60
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
60
60
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
31
0
0
16
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
24
0
8
0
16
16
0
0
0
31
8
0
8
% D
% Glu:
0
16
0
0
24
0
0
0
0
0
0
0
0
0
16
% E
% Phe:
77
0
8
0
0
0
0
0
0
24
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
16
0
0
16
0
85
0
0
70
0
0
0
16
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
16
0
0
0
16
0
0
24
% K
% Leu:
0
0
0
0
16
0
0
0
8
31
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
8
24
0
0
0
16
0
0
0
0
77
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
16
0
0
0
0
70
8
0
8
0
% R
% Ser:
0
0
47
62
0
0
0
39
0
0
0
8
0
16
0
% S
% Thr:
0
8
8
8
0
0
0
0
0
16
8
16
16
0
24
% T
% Val:
0
62
0
0
0
0
85
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
0
24
16
16
39
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _