KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM53
All Species:
3.03
Human Site:
T33
Identified Species:
5.56
UniProt:
Q6P2H8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2H8
NP_078863.2
277
31630
T33
P
G
G
K
E
A
E
T
R
Q
P
V
V
I
L
Chimpanzee
Pan troglodytes
XP_513099
204
23435
P11
F
S
E
S
L
G
I
P
S
L
R
V
L
A
Q
Rhesus Macaque
Macaca mulatta
XP_001093396
204
23354
P11
F
S
E
S
L
G
I
P
S
L
R
V
L
A
Q
Dog
Lupus familis
XP_539639
278
31512
A33
P
G
R
K
E
V
G
A
R
Q
P
L
V
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0Z3
276
31570
Q33
G
K
E
A
G
K
Q
Q
P
V
V
I
L
L
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJC8
285
32654
L33
R
E
P
V
V
I
L
L
G
W
G
G
C
K
D
Zebra Danio
Brachydanio rerio
Q6DHN0
281
32493
S38
I
L
L
G
W
A
G
S
R
D
K
H
L
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610178
343
39125
H74
D
H
D
G
E
D
S
H
V
P
I
V
M
L
L
Honey Bee
Apis mellifera
XP_392954
326
37186
D43
F
V
F
V
Y
K
E
D
K
R
P
V
I
V
L
Nematode Worm
Caenorhab. elegans
NP_491980
325
37453
E66
L
S
D
S
H
H
D
E
K
K
P
V
I
L
M
Sea Urchin
Strong. purpuratus
XP_788598
287
32857
R38
R
S
I
T
G
D
M
R
T
V
P
V
I
V
L
Poplar Tree
Populus trichocarpa
XP_002306371
443
48844
T169
C
L
S
E
K
S
R
T
V
V
V
L
L
G
W
Maize
Zea mays
NP_001146062
309
34480
V33
F
P
D
K
S
Q
T
V
V
V
L
L
G
W
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.2
71.8
88.8
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
54
48
N.A.
30.8
30.3
24
33.1
Protein Similarity:
100
73.2
72.5
92.8
N.A.
91.6
N.A.
N.A.
N.A.
N.A.
68.4
65.1
N.A.
48.9
48.4
42.1
51.9
P-Site Identity:
100
6.6
6.6
66.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
13.3
N.A.
20
26.6
13.3
20
P-Site Similarity:
100
13.3
13.3
73.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
26.6
N.A.
33.3
53.3
53.3
33.3
Percent
Protein Identity:
22.3
26.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
36.1
46.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
16
0
8
0
0
0
0
0
24
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
0
24
0
0
16
8
8
0
8
0
0
0
0
8
% D
% Glu:
0
8
24
8
24
0
16
8
0
0
0
0
0
0
0
% E
% Phe:
31
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
16
8
16
16
16
16
0
8
0
8
8
8
8
8
% G
% His:
0
8
0
0
8
8
0
8
0
0
0
8
0
0
0
% H
% Ile:
8
0
8
0
0
8
16
0
0
0
8
8
24
16
0
% I
% Lys:
0
8
0
24
8
16
0
0
16
8
8
0
0
8
8
% K
% Leu:
8
16
8
0
16
0
8
8
0
16
8
24
39
24
47
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
16
8
8
0
0
0
0
16
8
8
39
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
8
0
16
0
0
0
0
16
% Q
% Arg:
16
0
8
0
0
0
8
8
24
8
16
0
0
0
0
% R
% Ser:
0
31
8
24
8
8
8
8
16
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
8
16
8
0
0
0
0
0
0
% T
% Val:
0
8
0
16
8
8
0
8
24
31
16
54
16
16
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
8
0
0
0
8
8
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _