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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM53
All Species:
13.64
Human Site:
T9
Identified Species:
25
UniProt:
Q6P2H8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2H8
NP_078863.2
277
31630
T9
A
S
A
E
L
D
Y
T
I
E
I
P
D
Q
P
Chimpanzee
Pan troglodytes
XP_513099
204
23435
Rhesus Macaque
Macaca mulatta
XP_001093396
204
23354
Dog
Lupus familis
XP_539639
278
31512
T9
A
S
A
E
L
D
Y
T
I
E
I
P
D
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0Z3
276
31570
S9
A
S
A
E
L
D
Y
S
I
E
I
P
D
Q
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJC8
285
32654
T9
G
D
P
E
L
D
Y
T
I
E
F
P
E
P
S
Zebra Danio
Brachydanio rerio
Q6DHN0
281
32493
E14
D
Y
N
I
V
F
S
E
A
L
I
S
E
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610178
343
39125
F50
R
E
D
T
L
E
Y
F
I
K
F
P
K
P
S
Honey Bee
Apis mellifera
XP_392954
326
37186
S19
M
F
P
S
F
P
P
S
P
K
D
P
T
L
T
Nematode Worm
Caenorhab. elegans
NP_491980
325
37453
M42
R
H
V
P
E
P
K
M
M
I
H
L
S
K
S
Sea Urchin
Strong. purpuratus
XP_788598
287
32857
F14
H
V
T
F
P
T
N
F
S
K
S
R
E
V
S
Poplar Tree
Populus trichocarpa
XP_002306371
443
48844
R145
S
S
P
D
I
L
Y
R
W
H
L
P
E
P
S
Maize
Zea mays
NP_001146062
309
34480
S9
P
A
I
P
S
S
P
S
D
V
L
Y
R
W
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.2
71.8
88.8
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
54
48
N.A.
30.8
30.3
24
33.1
Protein Similarity:
100
73.2
72.5
92.8
N.A.
91.6
N.A.
N.A.
N.A.
N.A.
68.4
65.1
N.A.
48.9
48.4
42.1
51.9
P-Site Identity:
100
0
0
93.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
53.3
6.6
N.A.
26.6
6.6
0
0
P-Site Similarity:
100
0
0
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
60
26.6
N.A.
40
20
13.3
13.3
Percent
Protein Identity:
22.3
26.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
36.1
46.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
53.3
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
24
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
0
31
0
0
8
0
8
0
24
0
0
% D
% Glu:
0
8
0
31
8
8
0
8
0
31
0
0
31
8
0
% E
% Phe:
0
8
0
8
8
8
0
16
0
0
16
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
8
0
0
0
0
0
0
0
8
8
0
0
0
16
% H
% Ile:
0
0
8
8
8
0
0
0
39
8
31
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
24
0
0
8
16
0
% K
% Leu:
0
0
0
0
39
8
0
0
0
8
16
8
0
8
0
% L
% Met:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
24
16
8
16
16
0
8
0
0
54
0
24
24
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% Q
% Arg:
16
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% R
% Ser:
8
31
0
8
8
8
8
24
8
0
8
8
8
0
39
% S
% Thr:
0
0
8
8
0
8
0
24
0
0
0
0
8
0
8
% T
% Val:
0
8
8
0
8
0
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% W
% Tyr:
0
8
0
0
0
0
47
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _