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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM53
All Species:
17.88
Human Site:
Y8
Identified Species:
32.78
UniProt:
Q6P2H8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2H8
NP_078863.2
277
31630
Y8
M
A
S
A
E
L
D
Y
T
I
E
I
P
D
Q
Chimpanzee
Pan troglodytes
XP_513099
204
23435
Rhesus Macaque
Macaca mulatta
XP_001093396
204
23354
Dog
Lupus familis
XP_539639
278
31512
Y8
M
A
S
A
E
L
D
Y
T
I
E
I
P
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0Z3
276
31570
Y8
M
A
S
A
E
L
D
Y
S
I
E
I
P
D
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJC8
285
32654
Y8
M
G
D
P
E
L
D
Y
T
I
E
F
P
E
P
Zebra Danio
Brachydanio rerio
Q6DHN0
281
32493
S13
L
D
Y
N
I
V
F
S
E
A
L
I
S
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610178
343
39125
Y49
E
R
E
D
T
L
E
Y
F
I
K
F
P
K
P
Honey Bee
Apis mellifera
XP_392954
326
37186
P18
I
M
F
P
S
F
P
P
S
P
K
D
P
T
L
Nematode Worm
Caenorhab. elegans
NP_491980
325
37453
K41
T
R
H
V
P
E
P
K
M
M
I
H
L
S
K
Sea Urchin
Strong. purpuratus
XP_788598
287
32857
N13
Y
H
V
T
F
P
T
N
F
S
K
S
R
E
V
Poplar Tree
Populus trichocarpa
XP_002306371
443
48844
Y144
T
S
S
P
D
I
L
Y
R
W
H
L
P
E
P
Maize
Zea mays
NP_001146062
309
34480
P8
M
P
A
I
P
S
S
P
S
D
V
L
Y
R
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.2
71.8
88.8
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
54
48
N.A.
30.8
30.3
24
33.1
Protein Similarity:
100
73.2
72.5
92.8
N.A.
91.6
N.A.
N.A.
N.A.
N.A.
68.4
65.1
N.A.
48.9
48.4
42.1
51.9
P-Site Identity:
100
0
0
93.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
60
6.6
N.A.
26.6
6.6
0
0
P-Site Similarity:
100
0
0
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
66.6
33.3
N.A.
40
26.6
13.3
13.3
Percent
Protein Identity:
22.3
26.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
36.1
46.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
53.3
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
8
24
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
8
8
0
31
0
0
8
0
8
0
24
0
% D
% Glu:
8
0
8
0
31
8
8
0
8
0
31
0
0
31
8
% E
% Phe:
0
0
8
0
8
8
8
0
16
0
0
16
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
8
0
0
8
8
8
0
0
0
39
8
31
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
24
0
0
8
16
% K
% Leu:
8
0
0
0
0
39
8
0
0
0
8
16
8
0
8
% L
% Met:
39
8
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
24
16
8
16
16
0
8
0
0
54
0
24
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% Q
% Arg:
0
16
0
0
0
0
0
0
8
0
0
0
8
8
0
% R
% Ser:
0
8
31
0
8
8
8
8
24
8
0
8
8
8
0
% S
% Thr:
16
0
0
8
8
0
8
0
24
0
0
0
0
8
0
% T
% Val:
0
0
8
8
0
8
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% W
% Tyr:
8
0
8
0
0
0
0
47
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _