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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNCK
All Species:
9.09
Human Site:
S222
Identified Species:
15.38
UniProt:
Q6P2M8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2M8
NP_001034671
343
38500
S222
E
S
D
P
E
L
F
S
Q
I
L
R
A
S
Y
Chimpanzee
Pan troglodytes
XP_516263
370
41302
F227
D
E
N
D
A
K
L
F
E
Q
I
L
K
A
E
Rhesus Macaque
Macaca mulatta
XP_001084217
354
39458
P222
X
X
L
C
G
Y
P
P
F
Y
D
E
S
D
P
Dog
Lupus familis
XP_549361
278
31400
F166
I
L
R
A
S
Y
E
F
D
S
P
F
W
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYK9
343
38500
S222
E
S
D
P
E
L
F
S
Q
I
L
R
A
S
Y
Rat
Rattus norvegicus
O70150
343
38420
S222
E
S
D
P
E
L
F
S
Q
I
L
R
A
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510983
355
40054
F237
L
L
C
G
Y
P
P
F
Y
D
E
N
D
S
E
Chicken
Gallus gallus
XP_417986
455
50818
E250
E
T
E
S
K
L
F
E
K
I
K
E
G
Y
Y
Frog
Xenopus laevis
Q6GLS4
377
42906
E231
E
L
E
E
E
D
Y
E
S
H
D
K
N
L
F
Zebra Danio
Brachydanio rerio
Q7SY49
436
48676
N231
A
D
D
D
D
Y
E
N
H
D
K
N
L
F
R
Tiger Blowfish
Takifugu rubipres
Q9YGM4
421
47309
D231
E
E
D
S
D
S
R
D
K
N
L
F
L
K
I
Fruit Fly
Dros. melanogaster
Q00168
530
59901
L222
W
D
E
D
Q
H
R
L
Y
S
Q
I
K
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49101
513
58063
D275
E
I
E
K
G
I
F
D
A
I
L
H
E
E
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42396
490
55361
R232
E
S
E
I
G
I
F
R
K
I
L
Q
G
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61
88.6
76.6
N.A.
95.3
95.3
N.A.
75.2
47
40.3
35.5
37
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
77
90.6
78.7
N.A.
96.5
96.5
N.A.
85.3
60.2
58.3
53.2
54.6
42.8
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
0
N.A.
100
100
N.A.
6.6
33.3
13.3
6.6
20
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
6.6
0
N.A.
100
100
N.A.
6.6
60
40
20
33.3
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
29.4
N.A.
31
N.A.
N.A.
Protein Similarity:
N.A.
43.6
N.A.
45.3
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
0
0
8
0
0
0
22
15
0
% A
% Cys:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
36
22
15
8
0
15
8
15
15
0
8
15
8
% D
% Glu:
58
15
36
8
29
0
15
15
8
0
8
15
8
8
15
% E
% Phe:
0
0
0
0
0
0
43
22
8
0
0
15
0
8
8
% F
% Gly:
0
0
0
8
22
0
0
0
0
0
0
0
15
0
8
% G
% His:
0
0
0
0
0
8
0
0
8
8
0
8
0
0
0
% H
% Ile:
8
8
0
8
0
15
0
0
0
43
8
8
0
0
15
% I
% Lys:
0
0
0
8
8
8
0
0
22
0
15
8
15
15
0
% K
% Leu:
8
22
8
0
0
29
8
8
0
0
43
8
15
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
8
0
15
8
0
0
% N
% Pro:
0
0
0
22
0
8
15
8
0
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
8
0
0
0
22
8
8
8
0
0
0
% Q
% Arg:
0
0
8
0
0
0
15
8
0
0
0
22
0
0
8
% R
% Ser:
0
29
0
15
8
8
0
22
8
15
0
0
8
29
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
8
22
8
0
15
8
0
0
0
8
29
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _