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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNCK All Species: 22.73
Human Site: T8 Identified Species: 38.46
UniProt: Q6P2M8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P2M8 NP_001034671 343 38500 T8 M L L L K K H T E D I S S V Y
Chimpanzee Pan troglodytes XP_516263 370 41302 A13 E G P R W K Q A E D I R D I Y
Rhesus Macaque Macaca mulatta XP_001084217 354 39458 T8 M L L L K K H T E D I S S V Y
Dog Lupus familis XP_549361 278 31400
Cat Felis silvestris
Mouse Mus musculus Q9QYK9 343 38500 T8 M L L L K K Q T E D I S S V Y
Rat Rattus norvegicus O70150 343 38420 T8 M L L L K K Q T E D I S S V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510983 355 40054 T33 G K A W K K K T E D I T S V Y
Chicken Gallus gallus XP_417986 455 50818 T37 S S S W K K Q T S N I R K T F
Frog Xenopus laevis Q6GLS4 377 42906 P17 D K K D Y N H P T E V S D R Y
Zebra Danio Brachydanio rerio Q7SY49 436 48676 P17 E K K D Y N S P T E I T D K Y
Tiger Blowfish Takifugu rubipres Q9YGM4 421 47309 P17 E K K D Y N S P S E V T D K Y
Fruit Fly Dros. melanogaster Q00168 530 59901 K22 D I K E E L G K G A F S I V K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49101 513 58063 Y58 D T I L G K Q Y E D V R S V Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42396 490 55361 T15 R W V L P Y K T K N V E D N Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61 88.6 76.6 N.A. 95.3 95.3 N.A. 75.2 47 40.3 35.5 37 30.1 N.A. N.A. N.A.
Protein Similarity: 100 77 90.6 78.7 N.A. 96.5 96.5 N.A. 85.3 60.2 58.3 53.2 54.6 42.8 N.A. N.A. N.A.
P-Site Identity: 100 33.3 100 0 N.A. 93.3 93.3 N.A. 60 26.6 20 13.3 6.6 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 40 100 0 N.A. 93.3 93.3 N.A. 66.6 40 33.3 26.6 26.6 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 29.4 N.A. 31 N.A. N.A.
Protein Similarity: N.A. 43.6 N.A. 45.3 N.A. N.A.
P-Site Identity: N.A. 46.6 N.A. 20 N.A. N.A.
P-Site Similarity: N.A. 60 N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 8 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 22 0 0 22 0 0 0 0 0 50 0 0 36 0 0 % D
% Glu: 22 0 0 8 8 0 0 0 50 22 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % F
% Gly: 8 8 0 0 8 0 8 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 22 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 0 0 0 58 0 8 8 0 % I
% Lys: 0 29 29 0 43 58 15 8 8 0 0 0 8 15 8 % K
% Leu: 0 29 29 43 0 8 0 0 0 0 0 0 0 0 0 % L
% Met: 29 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 22 0 0 0 15 0 0 0 8 0 % N
% Pro: 0 0 8 0 8 0 0 22 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 8 0 0 0 0 0 0 0 22 0 8 0 % R
% Ser: 8 8 8 0 0 0 15 0 15 0 0 43 43 0 0 % S
% Thr: 0 8 0 0 0 0 0 50 15 0 0 22 0 8 0 % T
% Val: 0 0 8 0 0 0 0 0 0 0 29 0 0 50 0 % V
% Trp: 0 8 0 15 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 22 8 0 8 0 0 0 0 0 0 79 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _