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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF8
All Species:
26.67
Human Site:
S364
Identified Species:
48.89
UniProt:
Q6P2Q9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2Q9
NP_006436.3
2335
273600
S364
N
P
I
S
H
R
H
S
V
K
S
Q
E
P
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117328
2324
271913
S364
N
P
I
S
H
R
H
S
V
K
S
Q
E
P
L
Dog
Lupus familis
XP_868467
2335
273550
F364
N
P
I
S
H
S
N
F
R
A
S
Q
E
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99PV0
2335
273598
S364
N
P
I
S
H
R
H
S
V
K
S
Q
E
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415805
2335
273614
S364
N
P
I
S
H
R
H
S
V
K
S
Q
E
P
L
Frog
Xenopus laevis
NP_001080253
2335
273603
S364
N
P
I
S
H
R
H
S
V
K
S
Q
E
P
L
Zebra Danio
Brachydanio rerio
NP_957270
2342
274356
S371
N
P
I
S
H
R
H
S
V
K
S
Q
E
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610735
2396
279559
A423
N
P
I
S
H
R
N
A
N
S
K
I
Q
E
P
Honey Bee
Apis mellifera
XP_624014
2374
277137
S403
N
P
I
S
H
R
N
S
L
K
T
V
E
P
Q
Nematode Worm
Caenorhab. elegans
P34369
2329
272009
L354
N
P
I
V
L
S
N
L
K
A
T
E
E
N
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002327417
2357
275373
K382
H
P
I
T
S
S
N
K
E
R
R
E
K
K
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178124
2382
278110
K410
H
P
I
S
N
T
N
K
E
K
R
E
R
K
V
Baker's Yeast
Sacchar. cerevisiae
P33334
2413
279485
I435
L
N
P
I
P
H
F
I
D
N
N
S
S
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
99.7
N.A.
99.9
N.A.
N.A.
N.A.
99.4
98.5
97.6
N.A.
89.4
90.4
86.5
N.A.
Protein Similarity:
100
N.A.
98.5
99.8
N.A.
99.9
N.A.
N.A.
N.A.
99.6
99.4
99
N.A.
94.1
95.2
94.3
N.A.
P-Site Identity:
100
N.A.
100
66.6
N.A.
100
N.A.
N.A.
N.A.
100
100
100
N.A.
40
66.6
33.3
N.A.
P-Site Similarity:
100
N.A.
100
73.3
N.A.
100
N.A.
N.A.
N.A.
100
100
100
N.A.
60
86.6
53.3
N.A.
Percent
Protein Identity:
82.4
N.A.
N.A.
81.4
60.6
N.A.
Protein Similarity:
91.3
N.A.
N.A.
90.6
75.7
N.A.
P-Site Identity:
13.3
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
60
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
16
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
16
0
0
24
70
8
0
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
16
0
0
0
70
8
47
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
93
8
0
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
16
8
62
8
0
8
16
0
% K
% Leu:
8
0
0
0
8
0
0
8
8
0
0
0
0
8
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
77
8
0
0
8
0
47
0
8
8
8
0
0
8
8
% N
% Pro:
0
93
8
0
8
0
0
0
0
0
0
0
0
62
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
54
8
0
8
% Q
% Arg:
0
0
0
0
0
62
0
0
8
8
16
0
8
0
0
% R
% Ser:
0
0
0
77
8
24
0
54
0
8
54
8
8
0
0
% S
% Thr:
0
0
0
8
0
8
0
0
0
0
16
0
0
0
8
% T
% Val:
0
0
0
8
0
0
0
0
47
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _