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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENND1B
All Species:
17.58
Human Site:
S408
Identified Species:
55.24
UniProt:
Q6P3S1
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P3S1
NP_001136267.1
426
48260
S408
V
F
E
E
E
I
T
S
G
G
F
C
G
G
K
Chimpanzee
Pan troglodytes
XP_001137898
426
48274
S408
V
F
E
E
E
I
T
S
G
G
F
C
G
G
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547378
768
85414
S396
I
F
E
E
E
I
T
S
G
G
F
C
G
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3U1T9
425
48192
S408
I
F
E
E
E
I
T
S
G
G
F
C
G
G
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506128
788
87890
S414
V
F
E
E
E
I
T
S
G
G
F
C
G
G
N
Chicken
Gallus gallus
XP_422194
839
93195
A461
V
F
E
E
E
I
T
A
G
G
F
C
G
G
N
Frog
Xenopus laevis
Q68F67
1010
112359
A607
Y
Q
R
M
D
L
T
A
Q
E
R
T
R
T
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397549
694
78747
L597
S
K
Q
M
T
Q
S
L
H
I
P
E
M
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
41.5
N.A.
91.5
N.A.
N.A.
43
43.1
21.2
N.A.
N.A.
N.A.
22.3
N.A.
N.A.
Protein Similarity:
100
100
N.A.
45.1
N.A.
96.2
N.A.
N.A.
47.2
46
30.8
N.A.
N.A.
N.A.
37.3
N.A.
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
N.A.
N.A.
93.3
86.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
N.A.
N.A.
93.3
93.3
26.6
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
75
75
75
0
0
0
0
13
0
13
0
0
13
% E
% Phe:
0
75
0
0
0
0
0
0
0
0
75
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
75
75
0
0
75
88
0
% G
% His:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% H
% Ile:
25
0
0
0
0
75
0
0
0
13
0
0
0
0
13
% I
% Lys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
38
% K
% Leu:
0
0
0
0
0
13
0
13
0
0
0
0
0
0
0
% L
% Met:
0
0
0
25
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
38
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% P
% Gln:
0
13
13
0
0
13
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
13
0
0
0
0
0
0
0
13
0
13
0
0
% R
% Ser:
13
0
0
0
0
0
13
63
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
13
0
88
0
0
0
0
13
0
13
0
% T
% Val:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _