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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO42
All Species:
19.09
Human Site:
S421
Identified Species:
38.18
UniProt:
Q6P3S6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P3S6
NP_061867.1
717
77839
S421
R
A
Q
R
Q
T
P
S
G
S
R
E
G
S
L
Chimpanzee
Pan troglodytes
XP_001153379
717
77794
S421
R
A
Q
R
Q
T
P
S
G
S
R
E
G
S
L
Rhesus Macaque
Macaca mulatta
XP_001086461
716
77745
S421
R
A
Q
R
Q
T
P
S
G
S
R
E
G
S
L
Dog
Lupus familis
XP_852026
717
77933
S421
R
A
Q
R
Q
T
P
S
S
S
R
E
G
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDJ6
717
77758
S421
R
A
Q
R
Q
T
P
S
G
S
R
E
G
S
L
Rat
Rattus norvegicus
NP_001102161
352
38884
Y65
I
L
S
F
L
S
P
Y
Q
E
H
K
T
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521623
549
58732
P262
S
R
E
G
S
L
S
P
A
R
G
D
S
S
P
Chicken
Gallus gallus
XP_417619
704
76449
W408
A
P
C
V
N
G
R
W
G
T
L
R
P
R
A
Frog
Xenopus laevis
NP_001087902
690
75284
R394
K
R
S
H
S
P
V
R
A
P
D
E
A
P
C
Zebra Danio
Brachydanio rerio
NP_997904
619
66541
P332
Q
A
P
S
G
R
A
P
L
S
P
S
L
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611647
667
74412
I380
V
P
P
R
G
Y
R
I
P
V
P
D
R
R
L
Honey Bee
Apis mellifera
XP_396808
526
60182
Q239
K
P
Q
P
R
Y
G
Q
S
Q
I
E
L
G
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
97
N.A.
95.4
46.7
N.A.
71.2
90
78.3
64.8
N.A.
28.7
27.6
N.A.
N.A.
Protein Similarity:
100
99.8
99.5
98.7
N.A.
97.4
48.2
N.A.
74
92.7
84
71.2
N.A.
46.4
43.7
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
6.6
N.A.
6.6
6.6
6.6
13.3
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
26.6
N.A.
20
13.3
13.3
26.6
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
50
0
0
0
0
9
0
17
0
0
0
9
9
17
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
17
0
0
9
% D
% Glu:
0
0
9
0
0
0
0
0
0
9
0
59
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
17
9
9
0
42
0
9
0
42
9
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% I
% Lys:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
9
0
0
9
9
0
0
9
0
9
0
17
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
25
17
9
0
9
50
17
9
9
17
0
9
9
9
% P
% Gln:
9
0
50
0
42
0
0
9
9
9
0
0
0
0
0
% Q
% Arg:
42
17
0
50
9
9
17
9
0
9
42
9
9
17
0
% R
% Ser:
9
0
17
9
17
9
9
42
17
50
0
9
9
50
9
% S
% Thr:
0
0
0
0
0
42
0
0
0
9
0
0
9
0
0
% T
% Val:
9
0
0
9
0
0
9
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
17
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _