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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM173B
All Species:
13.33
Human Site:
S18
Identified Species:
26.67
UniProt:
Q6P4H8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P4H8
NP_954584.2
233
26110
S18
T
L
K
E
E
S
Q
S
R
H
V
L
P
A
S
Chimpanzee
Pan troglodytes
XP_517628
233
26119
S18
T
L
K
E
E
S
Q
S
R
H
V
L
P
A
N
Rhesus Macaque
Macaca mulatta
XP_001084545
221
24613
S18
T
L
T
E
E
S
Q
S
R
H
V
L
P
A
S
Dog
Lupus familis
XP_535794
229
25145
L16
E
I
L
E
E
T
Q
L
G
C
V
L
P
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1Z3
247
27379
A13
T
P
E
E
E
R
Q
A
G
P
V
L
P
T
S
Rat
Rattus norvegicus
NP_001102648
216
24034
S13
T
P
E
E
E
R
Q
S
G
C
V
L
P
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426055
218
24396
R20
A
G
S
E
D
G
S
R
R
R
R
W
G
L
W
Frog
Xenopus laevis
Q5I047
226
25459
L11
S
R
K
E
S
K
S
L
E
E
Y
S
I
V
S
Zebra Danio
Brachydanio rerio
NP_001007392
159
17300
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650957
204
22470
A13
E
S
A
P
N
P
L
A
K
T
P
K
S
G
M
Honey Bee
Apis mellifera
XP_624435
206
23152
Y11
I
F
V
N
G
I
N
Y
I
I
T
N
N
V
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794078
229
24965
S15
K
K
S
G
K
S
K
S
N
G
R
W
K
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
90.9
79.8
N.A.
71.2
75.1
N.A.
N.A.
65.2
63
43.3
N.A.
39.9
43.3
N.A.
34.7
Protein Similarity:
100
100
92.2
84.9
N.A.
78.5
80.6
N.A.
N.A.
75.9
75.9
51.5
N.A.
53.6
57
N.A.
49.3
P-Site Identity:
100
93.3
93.3
46.6
N.A.
53.3
60
N.A.
N.A.
13.3
20
0
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
93.3
60
N.A.
66.6
66.6
N.A.
N.A.
20
26.6
0
N.A.
13.3
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
17
0
0
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
17
0
17
67
50
0
0
0
9
9
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
9
9
9
0
0
25
9
0
0
9
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% H
% Ile:
9
9
0
0
0
9
0
0
9
9
0
0
9
0
0
% I
% Lys:
9
9
25
0
9
9
9
0
9
0
0
9
9
9
0
% K
% Leu:
0
25
9
0
0
0
9
17
0
0
0
50
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
9
9
0
9
0
9
0
0
9
9
0
17
% N
% Pro:
0
17
0
9
0
9
0
0
0
9
9
0
50
0
0
% P
% Gln:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
17
0
9
34
9
17
0
0
0
0
% R
% Ser:
9
9
17
0
9
34
17
42
0
0
0
9
9
0
50
% S
% Thr:
42
0
9
0
0
9
0
0
0
9
9
0
0
25
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
50
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _