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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM173B
All Species:
14.24
Human Site:
S212
Identified Species:
28.48
UniProt:
Q6P4H8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P4H8
NP_954584.2
233
26110
S212
T
V
W
A
Y
D
A
S
T
F
R
G
R
E
K
Chimpanzee
Pan troglodytes
XP_517628
233
26119
S212
T
V
W
A
Y
D
A
S
T
F
R
G
R
E
K
Rhesus Macaque
Macaca mulatta
XP_001084545
221
24613
W193
C
R
F
P
F
P
H
W
T
P
D
H
V
T
G
Dog
Lupus familis
XP_535794
229
25145
S210
T
V
W
A
Y
D
I
S
T
L
R
G
K
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1Z3
247
27379
S207
T
V
W
A
Y
D
M
S
A
Q
R
G
R
G
G
Rat
Rattus norvegicus
NP_001102648
216
24034
T193
P
H
W
T
P
D
H
T
T
G
E
G
I
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426055
218
24396
Y197
G
I
D
T
V
W
A
Y
D
L
K
H
S
G
G
Frog
Xenopus laevis
Q5I047
226
25459
G204
T
V
W
T
Y
D
L
G
A
F
R
K
V
S
D
Zebra Danio
Brachydanio rerio
NP_001007392
159
17300
K140
F
Y
I
S
D
L
W
K
F
F
R
V
H
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650957
204
22470
L183
C
R
F
P
L
P
S
L
E
H
V
K
I
I
E
Honey Bee
Apis mellifera
XP_624435
206
23152
T182
A
C
R
F
P
L
P
T
M
T
E
I
K
I
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794078
229
24965
P189
S
V
V
A
C
R
F
P
I
P
N
W
E
P
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
90.9
79.8
N.A.
71.2
75.1
N.A.
N.A.
65.2
63
43.3
N.A.
39.9
43.3
N.A.
34.7
Protein Similarity:
100
100
92.2
84.9
N.A.
78.5
80.6
N.A.
N.A.
75.9
75.9
51.5
N.A.
53.6
57
N.A.
49.3
P-Site Identity:
100
100
6.6
66.6
N.A.
66.6
26.6
N.A.
N.A.
6.6
46.6
13.3
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
20
73.3
N.A.
66.6
40
N.A.
N.A.
20
46.6
33.3
N.A.
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
42
0
0
25
0
17
0
0
0
0
0
0
% A
% Cys:
17
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
50
0
0
9
0
9
0
0
9
9
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
17
0
9
17
9
% E
% Phe:
9
0
17
9
9
0
9
0
9
34
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
9
0
9
0
42
0
17
25
% G
% His:
0
9
0
0
0
0
17
0
0
9
0
17
9
0
9
% H
% Ile:
0
9
9
0
0
0
9
0
9
0
0
9
17
17
9
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
9
17
17
0
17
% K
% Leu:
0
0
0
0
9
17
9
9
0
17
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
9
0
0
17
17
17
9
9
0
17
0
0
0
9
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% Q
% Arg:
0
17
9
0
0
9
0
0
0
0
50
0
25
9
9
% R
% Ser:
9
0
0
9
0
0
9
34
0
0
0
0
9
9
0
% S
% Thr:
42
0
0
25
0
0
0
17
42
9
0
0
0
9
9
% T
% Val:
0
50
9
0
9
0
0
0
0
0
9
9
17
0
0
% V
% Trp:
0
0
50
0
0
9
9
9
0
0
0
9
0
0
0
% W
% Tyr:
0
9
0
0
42
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _