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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM173B
All Species:
26.97
Human Site:
T150
Identified Species:
53.94
UniProt:
Q6P4H8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P4H8
NP_954584.2
233
26110
T150
I
S
D
L
W
K
V
T
F
S
Q
Y
S
N
V
Chimpanzee
Pan troglodytes
XP_517628
233
26119
T150
I
S
D
L
W
K
V
T
F
S
Q
Y
S
N
V
Rhesus Macaque
Macaca mulatta
XP_001084545
221
24613
T150
I
S
D
L
W
K
V
T
F
S
Q
Y
S
N
V
Dog
Lupus familis
XP_535794
229
25145
T148
I
S
D
L
W
K
V
T
F
S
Q
Y
S
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1Z3
247
27379
T145
I
S
D
L
W
K
V
T
F
A
Q
Y
S
N
V
Rat
Rattus norvegicus
NP_001102648
216
24034
T145
I
S
D
L
W
K
V
T
F
A
Q
Y
S
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426055
218
24396
E158
P
Q
M
M
P
E
L
E
K
K
L
K
E
E
L
Frog
Xenopus laevis
Q5I047
226
25459
S142
V
S
D
L
W
K
V
S
F
S
R
Y
R
N
V
Zebra Danio
Brachydanio rerio
NP_001007392
159
17300
G102
V
I
A
A
A
K
R
G
F
K
A
V
G
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650957
204
22470
N145
K
F
D
I
K
D
Y
N
F
V
V
I
F
G
V
Honey Bee
Apis mellifera
XP_624435
206
23152
R143
L
W
K
H
N
L
K
R
Y
N
N
I
V
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794078
229
24965
D150
R
T
N
L
W
N
V
D
L
S
K
F
D
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
90.9
79.8
N.A.
71.2
75.1
N.A.
N.A.
65.2
63
43.3
N.A.
39.9
43.3
N.A.
34.7
Protein Similarity:
100
100
92.2
84.9
N.A.
78.5
80.6
N.A.
N.A.
75.9
75.9
51.5
N.A.
53.6
57
N.A.
49.3
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
0
73.3
13.3
N.A.
20
0
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
26.6
93.3
20
N.A.
26.6
20
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
0
0
0
0
17
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
67
0
0
9
0
9
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
9
0
9
0
0
0
0
9
9
9
% E
% Phe:
0
9
0
0
0
0
0
0
75
0
0
9
9
9
9
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
9
9
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
9
0
9
0
0
0
0
0
0
0
17
0
0
9
% I
% Lys:
9
0
9
0
9
67
9
0
9
17
9
9
0
0
0
% K
% Leu:
9
0
0
67
0
9
9
0
9
0
9
0
0
9
9
% L
% Met:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
9
0
9
0
9
9
0
0
59
0
% N
% Pro:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
50
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
9
9
0
0
9
0
9
0
0
% R
% Ser:
0
59
0
0
0
0
0
9
0
50
0
0
50
0
0
% S
% Thr:
0
9
0
0
0
0
0
50
0
0
0
0
0
0
0
% T
% Val:
17
0
0
0
0
0
67
0
0
9
9
9
9
9
67
% V
% Trp:
0
9
0
0
67
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
9
0
0
59
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _