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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFAIP8L2
All Species:
37.58
Human Site:
S139
Identified Species:
75.15
UniProt:
Q6P589
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P589
NP_078851.2
184
20556
S139
E
H
H
L
T
P
K
S
H
G
R
I
R
H
V
Chimpanzee
Pan troglodytes
XP_001152187
210
24367
S163
Q
R
H
L
T
A
K
S
H
G
R
V
N
N
V
Rhesus Macaque
Macaca mulatta
XP_001089116
380
42298
S333
Q
R
H
L
T
A
K
S
H
G
R
V
N
N
V
Dog
Lupus familis
XP_540310
184
20501
S139
E
H
H
L
T
P
K
S
H
G
R
I
R
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8Y7
184
20596
S139
E
H
H
L
T
P
K
S
H
D
R
I
R
H
V
Rat
Rattus norvegicus
Q6AYJ8
184
20732
S139
E
H
H
L
T
P
K
S
H
D
R
I
R
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507123
184
20069
S139
Q
R
H
L
T
P
K
S
L
G
R
I
R
H
V
Chicken
Gallus gallus
Q5ZJU8
186
21516
S139
S
S
H
L
T
A
K
S
H
S
R
I
N
H
V
Frog
Xenopus laevis
Q6P7I6
186
21638
S139
E
K
H
L
T
P
K
S
H
G
R
I
Q
H
V
Zebra Danio
Brachydanio rerio
Q7T364
186
21282
S139
N
T
H
L
T
T
K
S
H
G
R
I
N
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KVH9
188
21368
S141
Q
P
H
L
T
E
K
S
L
G
R
I
D
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0V7W6
389
42500
I307
G
K
T
V
V
L
G
I
D
K
H
L
T
P
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48
27.8
93.4
N.A.
94
92.3
N.A.
76
56.9
60.2
61.2
N.A.
38.8
N.A.
N.A.
N.A.
Protein Similarity:
100
68.5
38.6
95.1
N.A.
96.7
95.6
N.A.
84.2
80.6
79.5
77.9
N.A.
62.7
N.A.
N.A.
N.A.
P-Site Identity:
100
60
60
93.3
N.A.
93.3
93.3
N.A.
80
66.6
86.6
73.3
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
80
93.3
N.A.
93.3
93.3
N.A.
86.6
66.6
93.3
73.3
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
17
0
0
9
0
0
% D
% Glu:
42
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
9
0
0
67
0
0
0
0
0
% G
% His:
0
34
92
0
0
0
0
0
75
0
9
0
0
59
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
75
0
0
0
% I
% Lys:
0
17
0
0
0
0
92
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
92
0
9
0
0
17
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
34
17
0
% N
% Pro:
0
9
0
0
0
50
0
0
0
0
0
0
0
9
0
% P
% Gln:
34
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
25
0
0
0
0
0
0
0
0
92
0
42
9
0
% R
% Ser:
9
9
0
0
0
0
0
92
0
9
0
0
0
0
0
% S
% Thr:
0
9
9
0
92
9
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
9
9
0
0
0
0
0
0
17
0
0
100
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _