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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFAIP8L2
All Species:
38.79
Human Site:
S46
Identified Species:
77.58
UniProt:
Q6P589
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P589
NP_078851.2
184
20556
S46
L
D
E
L
Y
R
V
S
K
E
Y
T
H
S
R
Chimpanzee
Pan troglodytes
XP_001152187
210
24367
T70
L
D
E
L
Y
R
V
T
R
E
Y
T
Q
N
K
Rhesus Macaque
Macaca mulatta
XP_001089116
380
42298
T240
L
D
E
L
Y
R
V
T
R
E
Y
T
Q
N
K
Dog
Lupus familis
XP_540310
184
20501
S46
L
D
E
L
Y
R
V
S
K
E
Y
T
H
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8Y7
184
20596
S46
L
D
E
L
Y
R
V
S
K
E
Y
T
H
S
R
Rat
Rattus norvegicus
Q6AYJ8
184
20732
S46
L
D
E
L
Y
R
V
S
K
E
Y
T
H
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507123
184
20069
S46
L
D
E
L
Y
R
V
S
K
A
Y
T
R
S
R
Chicken
Gallus gallus
Q5ZJU8
186
21516
T46
L
D
E
L
Y
R
A
T
K
E
Y
T
H
N
R
Frog
Xenopus laevis
Q6P7I6
186
21638
S46
L
D
E
L
Y
R
V
S
K
E
Y
T
K
N
K
Zebra Danio
Brachydanio rerio
Q7T364
186
21282
S46
L
D
E
L
Y
R
V
S
K
E
Y
T
G
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KVH9
188
21368
C48
L
D
N
L
Y
R
L
C
K
M
H
T
G
N
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0V7W6
389
42500
A69
K
I
D
S
G
P
L
A
R
F
P
R
I
L
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48
27.8
93.4
N.A.
94
92.3
N.A.
76
56.9
60.2
61.2
N.A.
38.8
N.A.
N.A.
N.A.
Protein Similarity:
100
68.5
38.6
95.1
N.A.
96.7
95.6
N.A.
84.2
80.6
79.5
77.9
N.A.
62.7
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
66.6
100
N.A.
100
100
N.A.
86.6
80
80
86.6
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
86.6
93.3
93.3
93.3
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
92
9
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
84
0
0
0
0
0
0
75
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
17
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
42
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
75
0
0
0
9
0
34
% K
% Leu:
92
0
0
92
0
0
17
0
0
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
50
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% Q
% Arg:
0
0
0
0
0
92
0
0
25
0
0
9
9
0
59
% R
% Ser:
0
0
0
9
0
0
0
59
0
0
0
0
0
42
0
% S
% Thr:
0
0
0
0
0
0
0
25
0
0
0
92
0
0
0
% T
% Val:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
92
0
0
0
0
0
84
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _