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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
20.3
Human Site:
S309
Identified Species:
31.9
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
S309
A
A
L
A
S
S
P
S
E
G
W
L
R
T
K
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
S309
A
A
L
A
S
S
P
S
E
G
W
L
R
T
K
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S422
A
A
L
A
G
S
P
S
D
G
W
L
R
T
R
Dog
Lupus familis
XP_548434
951
104664
S371
A
A
L
A
G
S
P
S
Q
G
W
L
R
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
S302
A
V
L
A
G
S
P
S
E
S
W
L
R
T
R
Rat
Rattus norvegicus
O08874
985
112050
W360
T
S
V
A
L
P
G
W
S
P
S
E
N
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
G409
A
T
V
L
G
S
P
G
E
S
R
P
W
S
R
Chicken
Gallus gallus
XP_422357
1013
114806
W385
T
S
V
T
L
P
G
W
S
P
N
E
V
R
T
Frog
Xenopus laevis
Q7ZX15
486
56292
E17
G
W
L
Q
K
R
G
E
Y
I
K
T
W
R
P
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
G348
S
N
M
S
S
A
P
G
S
P
S
D
S
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
S165
T
F
C
D
H
C
G
S
L
L
Y
G
L
I
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
G222
D
V
V
W
K
C
P
G
N
K
A
D
A
V
E
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
S220
E
E
I
S
N
E
I
S
A
I
M
K
L
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
A297
W
L
L
L
S
D
I
A
E
E
I
R
K
K
K
Red Bread Mold
Neurospora crassa
P87253
1142
127954
T383
P
Q
F
A
A
P
P
T
S
P
G
S
Q
E
Q
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
80
73.3
N.A.
73.3
6.6
N.A.
26.6
0
6.6
13.3
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
20
N.A.
46.6
13.3
6.6
40
N.A.
20
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
27
0
47
7
7
0
7
7
0
7
0
7
0
0
% A
% Cys:
0
0
7
0
0
14
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
7
0
0
7
0
0
14
0
7
0
% D
% Glu:
7
7
0
0
0
7
0
7
34
7
0
14
0
7
7
% E
% Phe:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
27
0
27
20
0
27
7
7
0
7
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
14
0
0
14
7
0
0
7
0
% I
% Lys:
0
0
0
0
14
0
0
0
0
7
7
7
7
14
27
% K
% Leu:
0
7
47
14
14
0
0
0
7
7
0
34
14
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
7
0
0
7
0
0
0
7
0
7
0
7
0
0
% N
% Pro:
7
0
0
0
0
20
60
0
0
27
0
7
0
0
7
% P
% Gln:
0
7
0
7
0
0
0
0
7
0
0
0
7
0
7
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
7
7
34
20
27
% R
% Ser:
7
14
0
14
27
40
0
47
27
14
14
7
7
7
20
% S
% Thr:
20
7
0
7
0
0
0
7
0
0
0
7
0
27
7
% T
% Val:
0
14
27
0
0
0
0
0
0
0
0
0
7
7
0
% V
% Trp:
7
7
0
7
0
0
0
14
0
0
34
0
14
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _