Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN3 All Species: 12.73
Human Site: S488 Identified Species: 20
UniProt: Q6P5Z2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P5Z2 NP_037487.2 889 99421 S488 P T T L R E A S D P A T P S N
Chimpanzee Pan troglodytes XP_001159776 886 99121 S485 P T T L R E A S D P A T P S N
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 S601 P T T S R E A S D P A T P S N
Dog Lupus familis XP_548434 951 104664 A550 P A T P R G A A E P A S P S N
Cat Felis silvestris
Mouse Mus musculus Q8K045 878 97863 G477 R P S T A V C G T P S A A S P
Rat Rattus norvegicus O08874 985 112050 T552 V P V V D A R T P E L A P P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 A586 T P A H A P A A R V A S A P A
Chicken Gallus gallus XP_422357 1013 114806 D624 S S E M K A P D M P A Q D D V
Frog Xenopus laevis Q7ZX15 486 56292 D156 H P K V T M N D F D Y L K L L
Zebra Danio Brachydanio rerio XP_697542 940 106140 T540 L S P P S V S T P P S T G D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 N304 K C S L L D F N F I K V L G K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 S364 S G T T S S R S A S K V P G G
Sea Urchin Strong. purpuratus XP_787090 799 90414 F377 P P I Q R L S F G E A D S S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 R607 P S P Q K V G R D S P T K Q H
Red Bread Mold Neurospora crassa P87253 1142 127954 N734 Y N P A D Y A N I D A Y S S P
Conservation
Percent
Protein Identity: 100 97.7 81.5 84.2 N.A. 83.2 49.9 N.A. 64.2 48.9 26.2 52.2 N.A. 28 N.A. 29.1 41.5
Protein Similarity: 100 97.8 82.9 87.6 N.A. 88.4 63.6 N.A. 72.9 63 36.6 67.6 N.A. 41.5 N.A. 43.9 58.2
P-Site Identity: 100 100 93.3 60 N.A. 13.3 6.6 N.A. 13.3 13.3 0 13.3 N.A. 6.6 N.A. 20 26.6
P-Site Similarity: 100 100 93.3 80 N.A. 26.6 20 N.A. 26.6 33.3 6.6 46.6 N.A. 26.6 N.A. 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.2 27.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 43.2
P-Site Identity: N.A. N.A. N.A. N.A. 20 20
P-Site Similarity: N.A. N.A. N.A. N.A. 40 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 7 14 14 40 14 7 0 54 14 14 0 14 % A
% Cys: 0 7 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 14 7 0 14 27 14 0 7 7 14 0 % D
% Glu: 0 0 7 0 0 20 0 0 7 14 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 7 7 14 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 0 7 7 7 7 0 0 0 7 14 7 % G
% His: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 7 0 0 0 0 0 7 7 0 0 0 0 0 % I
% Lys: 7 0 7 0 14 0 0 0 0 0 14 0 14 0 7 % K
% Leu: 7 0 0 20 7 7 0 0 0 0 7 7 7 7 7 % L
% Met: 0 0 0 7 0 7 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 7 14 0 0 0 0 0 0 27 % N
% Pro: 40 34 20 14 0 7 7 0 14 47 7 0 40 14 14 % P
% Gln: 0 0 0 14 0 0 0 0 0 0 0 7 0 7 0 % Q
% Arg: 7 0 0 0 34 0 14 7 7 0 0 0 0 0 0 % R
% Ser: 14 20 14 7 14 7 14 27 0 14 14 14 14 47 7 % S
% Thr: 7 20 34 14 7 0 0 14 7 0 0 34 0 0 0 % T
% Val: 7 0 7 14 0 20 0 0 0 7 0 14 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 7 0 0 0 0 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _