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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN3 All Species: 22.08
Human Site: S883 Identified Species: 34.69
UniProt: Q6P5Z2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P5Z2 NP_037487.2 889 99421 S883 F R D F D F V S E R F L E P _
Chimpanzee Pan troglodytes XP_001159776 886 99121 S880 F R D F D F V S E R F L E P _
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 S1005 F R D F D F V S E R F L E P _
Dog Lupus familis XP_548434 951 104664 S945 F R D F D F V S E G F L G P _
Cat Felis silvestris
Mouse Mus musculus Q8K045 878 97863 S872 F R D F D F V S E Q F L E S _
Rat Rattus norvegicus O08874 985 112050 L968 P R E P R I L L E E E Q E M F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 S987 F Q G F D F V S D R F L E A _
Chicken Gallus gallus XP_422357 1013 114806 R1004 E E E Q E M F R D F D Y I A D
Frog Xenopus laevis Q7ZX15 486 56292
Zebra Danio Brachydanio rerio XP_697542 940 106140 D933 E Q Q E F F A D F D F S A L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133
Sea Urchin Strong. purpuratus XP_787090 799 90414 D791 E E Q E H F K D F N Y I A D W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500
Red Bread Mold Neurospora crassa P87253 1142 127954 S1136 Q E E F R G F S Y T A D F E _
Conservation
Percent
Protein Identity: 100 97.7 81.5 84.2 N.A. 83.2 49.9 N.A. 64.2 48.9 26.2 52.2 N.A. 28 N.A. 29.1 41.5
Protein Similarity: 100 97.8 82.9 87.6 N.A. 88.4 63.6 N.A. 72.9 63 36.6 67.6 N.A. 41.5 N.A. 43.9 58.2
P-Site Identity: 100 100 100 85.7 N.A. 85.7 20 N.A. 71.4 0 0 13.3 N.A. 0 N.A. 0 6.6
P-Site Similarity: 100 100 100 85.7 N.A. 92.8 33.3 N.A. 85.7 20 0 20 N.A. 0 N.A. 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.2 27.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 43.2
P-Site Identity: N.A. N.A. N.A. N.A. 0 14.2
P-Site Similarity: N.A. N.A. N.A. N.A. 0 21.4
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 0 0 0 7 0 14 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 34 0 40 0 0 14 14 7 7 7 0 7 7 % D
% Glu: 20 20 20 14 7 0 0 0 40 7 7 0 40 7 0 % E
% Phe: 40 0 0 47 7 54 14 0 14 7 47 0 7 0 7 % F
% Gly: 0 0 7 0 0 7 0 0 0 7 0 0 7 0 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 7 0 0 0 0 0 7 7 0 0 % I
% Lys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 7 7 0 0 0 40 0 7 0 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 7 0 0 7 0 0 0 0 0 0 0 0 0 27 0 % P
% Gln: 7 14 14 7 0 0 0 0 0 7 0 7 0 0 0 % Q
% Arg: 0 40 0 0 14 0 0 7 0 27 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 47 0 0 0 7 0 7 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 40 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 % _