Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN3 All Species: 12.73
Human Site: T482 Identified Species: 20
UniProt: Q6P5Z2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P5Z2 NP_037487.2 889 99421 T482 K G C P R T P T T L R E A S D
Chimpanzee Pan troglodytes XP_001159776 886 99121 T479 K G C P R T P T T L R E A S D
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 T595 K G C P R T P T T S R E A S D
Dog Lupus familis XP_548434 951 104664 A544 K A C P Q T P A T P R G A A E
Cat Felis silvestris
Mouse Mus musculus Q8K045 878 97863 P471 A S P P K G R P S T A V C G T
Rat Rattus norvegicus O08874 985 112050 P546 T P V P A T V P V V D A R T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 P580 L S P P S R T P A H A P A A R
Chicken Gallus gallus XP_422357 1013 114806 S618 G E I C E P S S E M K A P D M
Frog Xenopus laevis Q7ZX15 486 56292 P150 V A M S K G H P K V T M N D F
Zebra Danio Brachydanio rerio XP_697542 940 106140 S534 L P G S E P L S P P S V S T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 C298 G E T R P G K C S L L D F N F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 G358 Q I S E D D S G T T S S R S A
Sea Urchin Strong. purpuratus XP_787090 799 90414 P371 T A I R P R P P I Q R L S F G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 S601 R K H D K T P S P Q K V G R D
Red Bread Mold Neurospora crassa P87253 1142 127954 N728 S P Q Q R K Y N P A D Y A N I
Conservation
Percent
Protein Identity: 100 97.7 81.5 84.2 N.A. 83.2 49.9 N.A. 64.2 48.9 26.2 52.2 N.A. 28 N.A. 29.1 41.5
Protein Similarity: 100 97.8 82.9 87.6 N.A. 88.4 63.6 N.A. 72.9 63 36.6 67.6 N.A. 41.5 N.A. 43.9 58.2
P-Site Identity: 100 100 93.3 53.3 N.A. 6.6 13.3 N.A. 13.3 0 0 0 N.A. 6.6 N.A. 13.3 13.3
P-Site Similarity: 100 100 93.3 73.3 N.A. 20 26.6 N.A. 20 20 13.3 20 N.A. 26.6 N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.2 27.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 43.2
P-Site Identity: N.A. N.A. N.A. N.A. 20 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 20 0 0 7 0 0 7 7 7 14 14 40 14 7 % A
% Cys: 0 0 27 7 0 0 0 7 0 0 0 0 7 0 0 % C
% Asp: 0 0 0 7 7 7 0 0 0 0 14 7 0 14 27 % D
% Glu: 0 14 0 7 14 0 0 0 7 0 0 20 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 14 % F
% Gly: 14 20 7 0 0 20 0 7 0 0 0 7 7 7 7 % G
% His: 0 0 7 0 0 0 7 0 0 7 0 0 0 0 0 % H
% Ile: 0 7 14 0 0 0 0 0 7 0 0 0 0 0 7 % I
% Lys: 27 7 0 0 20 7 7 0 7 0 14 0 0 0 0 % K
% Leu: 14 0 0 0 0 0 7 0 0 20 7 7 0 0 0 % L
% Met: 0 0 7 0 0 0 0 0 0 7 0 7 0 0 7 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 0 7 14 0 % N
% Pro: 0 20 14 47 14 14 40 34 20 14 0 7 7 0 14 % P
% Gln: 7 0 7 7 7 0 0 0 0 14 0 0 0 0 0 % Q
% Arg: 7 0 0 14 27 14 7 0 0 0 34 0 14 7 7 % R
% Ser: 7 14 7 14 7 0 14 20 14 7 14 7 14 27 0 % S
% Thr: 14 0 7 0 0 40 7 20 34 14 7 0 0 14 7 % T
% Val: 7 0 7 0 0 0 7 0 7 14 0 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _