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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
14.85
Human Site:
Y517
Identified Species:
23.33
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
Y517
P
P
K
P
P
R
L
Y
L
P
Q
E
P
T
S
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
Y514
P
P
K
P
P
R
L
Y
L
P
Q
E
P
T
S
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
Y630
P
P
K
P
P
R
L
Y
L
P
Q
E
P
T
F
Dog
Lupus familis
XP_548434
951
104664
Y579
P
P
K
P
P
R
L
Y
L
P
R
E
P
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
R506
K
P
P
P
K
P
P
R
L
Y
L
Q
E
P
A
Rat
Rattus norvegicus
O08874
985
112050
R581
E
A
P
P
A
P
P
R
A
S
S
L
G
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
F615
P
P
K
P
P
R
L
F
L
P
L
E
P
V
A
Chicken
Gallus gallus
XP_422357
1013
114806
C653
K
L
Q
P
G
I
I
C
E
S
D
V
P
H
S
Frog
Xenopus laevis
Q7ZX15
486
56292
M185
A
T
G
R
Y
Y
A
M
K
I
L
R
K
E
V
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
Q569
P
P
R
L
H
L
A
Q
N
P
S
A
D
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
V333
D
E
I
Y
A
I
K
V
L
K
K
D
A
I
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
M393
K
G
S
F
G
K
V
M
L
A
E
R
K
G
T
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
V406
S
K
D
K
M
G
G
V
E
V
Q
D
A
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
I636
R
E
K
L
N
K
F
I
D
E
N
E
A
Y
L
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Y763
P
Q
Q
V
S
P
M
Y
Q
Q
N
P
Q
T
P
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
93.3
93.3
N.A.
20
6.6
N.A.
73.3
20
0
26.6
N.A.
6.6
N.A.
6.6
13.3
P-Site Similarity:
100
100
93.3
100
N.A.
33.3
6.6
N.A.
86.6
33.3
0
33.3
N.A.
20
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
14
0
14
0
7
7
0
7
20
0
14
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
0
0
0
7
0
7
14
7
0
0
% D
% Glu:
7
14
0
0
0
0
0
0
14
7
7
40
7
20
0
% E
% Phe:
0
0
0
7
0
0
7
7
0
0
0
0
0
0
7
% F
% Gly:
0
7
7
0
14
7
7
0
0
0
0
0
7
7
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
7
0
0
14
7
7
0
7
0
0
0
7
14
% I
% Lys:
20
7
40
7
7
14
7
0
7
7
7
0
14
0
0
% K
% Leu:
0
7
0
14
0
7
34
0
54
0
20
7
0
7
7
% L
% Met:
0
0
0
0
7
0
7
14
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
7
0
14
0
0
0
0
% N
% Pro:
47
47
14
54
34
20
14
0
0
40
0
7
40
7
7
% P
% Gln:
0
7
14
0
0
0
0
7
7
7
27
7
7
0
0
% Q
% Arg:
7
0
7
7
0
34
0
14
0
0
7
14
0
0
0
% R
% Ser:
7
0
7
0
7
0
0
0
0
14
14
0
0
0
40
% S
% Thr:
0
7
0
0
0
0
0
0
0
0
0
0
0
34
7
% T
% Val:
0
0
0
7
0
0
7
14
0
7
0
7
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
7
0
34
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _