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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALKBH5
All Species:
0.91
Human Site:
S245
Identified Species:
1.82
UniProt:
Q6P6C2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P6C2
NP_060228.3
458
51409
S245
R
V
S
E
P
V
L
S
L
P
V
R
R
G
S
Chimpanzee
Pan troglodytes
XP_001158112
378
42635
F204
R
P
I
V
S
V
S
F
F
S
D
S
A
L
C
Rhesus Macaque
Macaca mulatta
XP_001093803
378
42514
F204
R
P
I
V
S
V
S
F
F
S
D
S
A
L
C
Dog
Lupus familis
XP_851719
394
44237
V216
H
I
F
E
R
P
I
V
S
V
S
F
F
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3TSG4
395
44393
V217
H
I
F
E
R
P
I
V
S
V
S
F
F
S
D
Rat
Rattus norvegicus
XP_220525
395
44435
V217
H
I
F
E
R
P
I
V
S
V
S
F
F
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510391
150
17081
Chicken
Gallus gallus
XP_001233463
374
43339
S200
I
V
S
V
S
F
F
S
D
S
A
L
C
F
G
Frog
Xenopus laevis
Q6GPB5
360
41731
V186
F
E
R
P
I
V
S
V
S
F
F
S
D
S
A
Zebra Danio
Brachydanio rerio
NP_001070855
352
40573
I178
S
H
V
D
P
I
H
I
F
E
R
P
I
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784548
266
30371
V92
I
E
D
K
I
N
E
V
V
D
I
A
E
K
G
Poplar Tree
Populus trichocarpa
XP_002310305
245
27470
G71
I
V
N
I
Y
E
E
G
D
C
I
P
P
H
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.9
81.2
84.2
N.A.
82.5
82.9
N.A.
27.2
68.3
61.1
57.6
N.A.
N.A.
N.A.
N.A.
36
Protein Similarity:
100
81.2
82.3
85.3
N.A.
84.2
84.5
N.A.
29.6
73.3
69.6
67
N.A.
N.A.
N.A.
N.A.
45.2
P-Site Identity:
100
13.3
13.3
6.6
N.A.
6.6
6.6
N.A.
0
20
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
13.3
20
N.A.
20
20
N.A.
0
20
13.3
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
29.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
9
9
17
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
17
% C
% Asp:
0
0
9
9
0
0
0
0
17
9
17
0
9
0
25
% D
% Glu:
0
17
0
34
0
9
17
0
0
9
0
0
9
0
0
% E
% Phe:
9
0
25
0
0
9
9
17
25
9
9
25
25
9
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
17
% G
% His:
25
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
25
25
17
9
17
9
25
9
0
0
17
0
9
0
9
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
0
0
0
0
0
9
0
9
0
0
9
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
17
0
9
17
25
0
0
0
9
0
17
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
25
0
9
0
25
0
0
0
0
0
9
9
9
0
0
% R
% Ser:
9
0
17
0
25
0
25
17
34
25
25
25
0
34
17
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
25
9
25
0
34
0
42
9
25
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _