KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTUM
All Species:
8.48
Human Site:
S76
Identified Species:
20.74
UniProt:
Q6P988
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P988
NP_848588.3
496
55699
S76
Q
V
K
S
L
A
Q
S
L
Y
P
C
S
A
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112829
430
48621
G38
T
S
V
T
C
N
D
G
S
P
A
G
Y
Y
L
Dog
Lupus familis
XP_540493
588
64828
L135
P
A
K
T
A
R
L
L
A
P
A
P
G
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R116
503
56566
S83
Q
V
K
S
L
A
Q
S
L
Y
P
C
S
A
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510075
407
46064
F15
A
L
T
V
P
F
C
F
C
P
P
H
P
A
R
Chicken
Gallus gallus
XP_415640
525
58434
S105
S
P
H
V
V
E
F
S
L
H
P
C
S
A
Q
Frog
Xenopus laevis
NP_001085911
337
37916
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624550
593
67041
S155
Y
C
T
S
D
S
W
S
G
T
R
G
S
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794410
691
76679
A100
Q
L
Q
H
L
A
S
A
L
S
T
C
G
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141895
413
45378
R21
S
A
G
A
S
L
A
R
G
S
E
P
W
W
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.8
68.7
N.A.
89.8
N.A.
N.A.
68.1
72.7
55.2
N.A.
N.A.
N.A.
35
N.A.
32.2
Protein Similarity:
100
N.A.
85.4
74.1
N.A.
94.2
N.A.
N.A.
74.1
80.3
62.5
N.A.
N.A.
N.A.
51.9
N.A.
46.8
P-Site Identity:
100
N.A.
0
13.3
N.A.
100
N.A.
N.A.
13.3
46.6
0
N.A.
N.A.
N.A.
20
N.A.
33.3
P-Site Similarity:
100
N.A.
6.6
20
N.A.
100
N.A.
N.A.
26.6
60
0
N.A.
N.A.
N.A.
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
38.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
10
10
30
10
10
10
0
20
0
0
40
0
% A
% Cys:
0
10
0
0
10
0
10
0
10
0
0
40
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
10
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
0
0
0
0
10
20
0
0
20
20
0
0
% G
% His:
0
0
10
10
0
0
0
0
0
10
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
20
0
0
30
10
10
10
40
0
0
0
0
20
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
20
% N
% Pro:
10
10
0
0
10
0
0
0
0
30
40
20
10
0
0
% P
% Gln:
30
0
10
0
0
0
20
0
0
0
0
0
0
0
40
% Q
% Arg:
0
0
0
0
0
10
0
10
0
0
10
0
0
0
10
% R
% Ser:
20
10
0
30
10
10
10
40
10
20
0
0
40
0
0
% S
% Thr:
10
0
20
20
0
0
0
0
0
10
10
0
0
0
0
% T
% Val:
0
20
10
20
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
20
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _