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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTUM
All Species:
4.24
Human Site:
T427
Identified Species:
10.37
UniProt:
Q6P988
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P988
NP_848588.3
496
55699
T427
D
S
H
K
A
S
K
T
P
L
K
G
C
P
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112829
430
48621
C366
S
K
T
P
L
K
G
C
P
V
H
L
V
D
S
Dog
Lupus familis
XP_540493
588
64828
A519
D
G
H
K
A
S
K
A
P
L
K
G
C
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R116
503
56566
T434
D
S
H
K
A
S
K
T
P
M
K
G
C
P
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510075
407
46064
C343
G
K
G
P
V
K
G
C
P
I
H
L
I
D
S
Chicken
Gallus gallus
XP_415640
525
58434
A456
E
S
N
K
N
G
K
A
P
L
K
G
C
P
I
Frog
Xenopus laevis
NP_001085911
337
37916
D273
P
R
A
L
H
C
W
D
R
R
L
Q
E
T
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624550
593
67041
K515
V
I
P
S
G
K
R
K
C
V
Q
G
C
H
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794410
691
76679
N447
E
P
R
E
S
S
T
N
N
N
R
Q
Q
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141895
413
45378
I349
S
R
Q
N
G
L
F
I
N
S
C
F
A
H
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.8
68.7
N.A.
89.8
N.A.
N.A.
68.1
72.7
55.2
N.A.
N.A.
N.A.
35
N.A.
32.2
Protein Similarity:
100
N.A.
85.4
74.1
N.A.
94.2
N.A.
N.A.
74.1
80.3
62.5
N.A.
N.A.
N.A.
51.9
N.A.
46.8
P-Site Identity:
100
N.A.
6.6
86.6
N.A.
86.6
N.A.
N.A.
6.6
60
0
N.A.
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
13.3
86.6
N.A.
93.3
N.A.
N.A.
13.3
80
0
N.A.
N.A.
N.A.
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
38.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
30
0
0
20
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
10
0
20
10
0
10
0
50
0
10
% C
% Asp:
30
0
0
0
0
0
0
10
0
0
0
0
0
20
0
% D
% Glu:
20
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
20
% F
% Gly:
10
10
10
0
20
10
20
0
0
0
0
50
0
10
0
% G
% His:
0
0
30
0
10
0
0
0
0
0
20
0
0
20
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
10
0
0
10
0
10
% I
% Lys:
0
20
0
40
0
30
40
10
0
0
40
0
0
0
10
% K
% Leu:
0
0
0
10
10
10
0
0
0
30
10
20
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
10
10
0
0
10
20
10
0
0
0
0
10
% N
% Pro:
10
10
10
20
0
0
0
0
60
0
0
0
0
40
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
10
20
10
0
0
% Q
% Arg:
0
20
10
0
0
0
10
0
10
10
10
0
0
0
0
% R
% Ser:
20
30
0
10
10
40
0
0
0
10
0
0
0
0
20
% S
% Thr:
0
0
10
0
0
0
10
20
0
0
0
0
0
10
0
% T
% Val:
10
0
0
0
10
0
0
0
0
20
0
0
10
0
20
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _