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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOTUM
All Species:
13.64
Human Site:
Y297
Identified Species:
33.33
UniProt:
Q6P988
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P988
NP_848588.3
496
55699
Y297
A
I
R
R
G
I
R
Y
W
N
G
V
V
P
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112829
430
48621
E249
R
Q
F
Q
E
G
E
E
W
N
C
F
F
G
Y
Dog
Lupus familis
XP_540493
588
64828
Y389
A
I
R
R
G
I
R
Y
W
N
G
V
V
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R116
503
56566
Y304
A
I
R
R
G
I
R
Y
W
S
G
M
V
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510075
407
46064
K226
E
R
C
R
L
R
F
K
E
G
E
E
W
N
C
Chicken
Gallus gallus
XP_415640
525
58434
Y326
A
I
R
R
G
I
R
Y
W
N
G
I
V
P
E
Frog
Xenopus laevis
NP_001085911
337
37916
W156
I
Q
R
G
I
R
Y
W
S
S
M
V
P
E
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624550
593
67041
I375
H
C
W
E
Q
M
P
I
G
N
H
R
N
V
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794410
691
76679
L322
T
L
Q
R
G
T
K
L
W
N
S
L
V
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141895
413
45378
G232
L
D
T
V
D
V
S
G
R
R
E
M
R
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.8
68.7
N.A.
89.8
N.A.
N.A.
68.1
72.7
55.2
N.A.
N.A.
N.A.
35
N.A.
32.2
Protein Similarity:
100
N.A.
85.4
74.1
N.A.
94.2
N.A.
N.A.
74.1
80.3
62.5
N.A.
N.A.
N.A.
51.9
N.A.
46.8
P-Site Identity:
100
N.A.
13.3
100
N.A.
86.6
N.A.
N.A.
6.6
93.3
13.3
N.A.
N.A.
N.A.
6.6
N.A.
46.6
P-Site Similarity:
100
N.A.
20
100
N.A.
100
N.A.
N.A.
6.6
100
26.6
N.A.
N.A.
N.A.
13.3
N.A.
73.3
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
38.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
10
% C
% Asp:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
10
0
10
10
10
0
20
10
0
10
50
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
10
10
0
10
% F
% Gly:
0
0
0
10
50
10
0
10
10
10
40
0
0
10
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
40
0
0
10
40
0
10
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
10
0
0
10
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
10
20
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
60
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
10
50
0
% P
% Gln:
0
20
10
10
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
50
60
0
20
40
0
10
10
0
10
10
0
10
% R
% Ser:
0
0
0
0
0
0
10
0
10
20
10
0
0
10
0
% S
% Thr:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
30
50
10
0
% V
% Trp:
0
0
10
0
0
0
0
10
60
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
10
40
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _