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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDXDC1
All Species:
30
Human Site:
Y575
Identified Species:
50.77
UniProt:
Q6P996
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P996
NP_055842.2
788
86707
Y575
K
S
M
K
S
C
L
Y
V
G
M
A
S
D
N
Chimpanzee
Pan troglodytes
XP_510837
781
85910
Y568
K
S
M
K
S
C
L
Y
V
G
M
A
S
D
D
Rhesus Macaque
Macaca mulatta
XP_001109439
899
98732
Y675
K
S
M
K
S
C
L
Y
V
G
M
A
S
E
D
Dog
Lupus familis
XP_547116
788
86764
Y575
K
S
M
K
S
C
I
Y
V
G
M
A
S
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99K01
787
87317
Y575
K
S
M
K
S
C
I
Y
I
G
M
A
S
D
D
Rat
Rattus norvegicus
NP_001128433
785
86952
Y575
K
S
M
K
S
C
I
Y
I
G
M
A
S
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517129
771
84529
K565
G
P
E
F
G
R
K
K
N
C
I
Y
I
G
M
Chicken
Gallus gallus
XP_414728
791
88207
Y576
G
G
Q
K
N
C
V
Y
I
G
M
V
T
E
D
Frog
Xenopus laevis
Q6DF78
782
86187
Y566
G
A
E
K
N
C
I
Y
I
G
M
A
S
E
D
Zebra Danio
Brachydanio rerio
Q66HY8
751
83123
F544
N
F
S
G
G
P
E
F
S
E
E
K
N
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608450
852
91504
R634
T
D
G
L
I
C
V
R
F
G
M
V
T
H
E
Honey Bee
Apis mellifera
XP_393418
793
86822
H575
Y
A
P
P
T
W
I
H
V
M
T
D
Q
A
K
Nematode Worm
Caenorhab. elegans
NP_001123108
802
88931
W578
V
L
L
P
I
R
N
W
A
G
I
G
A
V
C
Sea Urchin
Strong. purpuratus
XP_796792
721
79028
R515
E
E
A
S
H
R
G
R
Y
Q
I
T
Q
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
83.7
90.9
N.A.
88.3
85.9
N.A.
69.1
69.9
65.6
59.9
N.A.
26.7
33.2
25
39.4
Protein Similarity:
100
97.9
85.2
94.1
N.A.
92
90.7
N.A.
80.9
81.2
79.6
73.3
N.A.
47.8
54.3
48.2
57.9
P-Site Identity:
100
93.3
86.6
86.6
N.A.
80
80
N.A.
0
33.3
46.6
0
N.A.
20
6.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
73.3
86.6
13.3
N.A.
33.3
33.3
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
0
0
0
0
0
8
0
0
50
8
8
8
% A
% Cys:
0
0
0
0
0
65
0
0
0
8
0
0
0
8
8
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
8
0
36
50
% D
% Glu:
8
8
15
0
0
0
8
0
0
8
8
0
0
22
8
% E
% Phe:
0
8
0
8
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
22
8
8
8
15
0
8
0
0
72
0
8
0
8
0
% G
% His:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
15
0
36
0
29
0
22
0
8
0
8
% I
% Lys:
43
0
0
58
0
0
8
8
0
0
0
8
0
0
8
% K
% Leu:
0
8
8
8
0
0
22
0
0
0
0
0
0
0
0
% L
% Met:
0
0
43
0
0
0
0
0
0
8
65
0
0
0
8
% M
% Asn:
8
0
0
0
15
0
8
0
8
0
0
0
8
0
8
% N
% Pro:
0
8
8
15
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
0
0
15
0
0
% Q
% Arg:
0
0
0
0
0
22
0
15
0
0
0
0
0
0
0
% R
% Ser:
0
43
8
8
43
0
0
0
8
0
0
0
50
0
0
% S
% Thr:
8
0
0
0
8
0
0
0
0
0
8
8
15
8
0
% T
% Val:
8
0
0
0
0
0
15
0
36
0
0
15
0
8
0
% V
% Trp:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
58
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _