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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1609 All Species: 22.42
Human Site: S142 Identified Species: 35.24
UniProt: Q6P9B6 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P9B6 NP_065998 456 51033 S142 G S V V H V L S H R Q E L R G
Chimpanzee Pan troglodytes XP_511145 551 60941 S237 G S V V H V L S H R Q E L R G
Rhesus Macaque Macaca mulatta XP_001110946 501 55814 S187 G S V V H V L S H R Q E L R G
Dog Lupus familis XP_546801 511 57349 N198 G S V V H V L N Y R Q E L R G
Cat Felis silvestris
Mouse Mus musculus Q8K0P3 455 50826 T140 A S V A H V L T H R H E L R G
Rat Rattus norvegicus XP_226525 475 52815 T140 A S V V H V L T H R H E L R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509591 593 64379 N276 T S V V H V L N Y R N E L K G
Chicken Gallus gallus Q5ZJX5 468 52097 S147 K S V V H V L S Y R K E L K G
Frog Xenopus laevis Q6DDZ9 460 52066 L139 I A A V I Y V L K Q Q S L L K
Zebra Danio Brachydanio rerio Q1LWV7 450 49931 L143 V Y A A V Q T L A H K G H L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609110 448 51415 W142 K N S G I K E W H D L G F N T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502405 399 45748 R119 C E G N K F T R E D Q V R L Y
Sea Urchin Strong. purpuratus XP_794130 468 51947 F141 T K E E L S Q F I A D I L S S
Poplar Tree Populus trichocarpa XP_002308447 422 46639 N141 E A S N P G L N S H R E I I N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196244 424 47406 S141 E S S D A E S S D Y K K M V D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.1 86.2 70.2 N.A. 65.1 60.8 N.A. 49.5 58.9 48.2 43.6 N.A. 31.3 N.A. 27.1 39.3
Protein Similarity: 100 82.4 88.2 79 N.A. 79.6 74.7 N.A. 60.7 76.7 67.8 63.3 N.A. 52.8 N.A. 46.2 53.8
P-Site Identity: 100 100 100 86.6 N.A. 73.3 80 N.A. 66.6 73.3 20 0 N.A. 6.6 N.A. 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 80 86.6 N.A. 86.6 93.3 40 6.6 N.A. 13.3 N.A. 6.6 6.6
Percent
Protein Identity: 25.4 N.A. N.A. 25.2 N.A. N.A.
Protein Similarity: 44 N.A. N.A. 42.7 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 14 14 14 7 0 0 0 7 7 0 0 0 0 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 0 7 14 7 0 0 0 7 % D
% Glu: 14 7 7 7 0 7 7 0 7 0 0 60 0 0 0 % E
% Phe: 0 0 0 0 0 7 0 7 0 0 0 0 7 0 0 % F
% Gly: 27 0 7 7 0 7 0 0 0 0 0 14 0 0 54 % G
% His: 0 0 0 0 54 0 0 0 40 14 14 0 7 0 0 % H
% Ile: 7 0 0 0 14 0 0 0 7 0 0 7 7 7 0 % I
% Lys: 14 7 0 0 7 7 0 0 7 0 20 7 0 14 7 % K
% Leu: 0 0 0 0 7 0 60 14 0 0 7 0 67 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 7 0 14 0 0 0 20 0 0 7 0 0 7 7 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 7 0 0 7 40 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 7 0 54 7 0 7 40 7 % R
% Ser: 0 60 20 0 0 7 7 34 7 0 0 7 0 7 7 % S
% Thr: 14 0 0 0 0 0 14 14 0 0 0 0 0 0 7 % T
% Val: 7 0 54 54 7 54 7 0 0 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 7 0 0 20 7 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _