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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1609 All Species: 16.67
Human Site: S332 Identified Species: 26.19
UniProt: Q6P9B6 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P9B6 NP_065998 456 51033 S332 F L F S I C P S M A V Y T H T
Chimpanzee Pan troglodytes XP_511145 551 60941 S427 F L F S V C P S M A V Y T H T
Rhesus Macaque Macaca mulatta XP_001110946 501 55814 S377 F L F S I C P S M A V Y T H T
Dog Lupus familis XP_546801 511 57349 R387 F L F S I S P R M A V Y T S T
Cat Felis silvestris
Mouse Mus musculus Q8K0P3 455 50826 R330 F L F S I A P R M A T H L H T
Rat Rattus norvegicus XP_226525 475 52815 R330 F L F S I A P R M A T Y T P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509591 593 64379 R466 F L F S I Y P R I E V Y P C T
Chicken Gallus gallus Q5ZJX5 468 52097 S340 F L F S V F P S L A V Y T Y T
Frog Xenopus laevis Q6DDZ9 460 52066 R334 F L F S I S P R L D V Y T Y T
Zebra Danio Brachydanio rerio Q1LWV7 450 49931 Y324 F L F S V F P Y M R V F T C T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609110 448 51415 A321 L L Y T L S P A M R C F S A T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502405 399 45748 L282 R T E N Y V Y L N Y Q Q Q Q H
Sea Urchin Strong. purpuratus XP_794130 468 51947 D323 F L F S L T S D L G V Y E T T
Poplar Tree Populus trichocarpa XP_002308447 422 46639 P305 S F L F Q L Y P K A S I F K P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196244 424 47406 K306 F L F Q L N P K A A I Y R P T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.1 86.2 70.2 N.A. 65.1 60.8 N.A. 49.5 58.9 48.2 43.6 N.A. 31.3 N.A. 27.1 39.3
Protein Similarity: 100 82.4 88.2 79 N.A. 79.6 74.7 N.A. 60.7 76.7 67.8 63.3 N.A. 52.8 N.A. 46.2 53.8
P-Site Identity: 100 93.3 100 80 N.A. 66.6 73.3 N.A. 60 73.3 66.6 60 N.A. 26.6 N.A. 0 46.6
P-Site Similarity: 100 100 100 80 N.A. 73.3 73.3 N.A. 66.6 93.3 80 73.3 N.A. 66.6 N.A. 6.6 60
Percent
Protein Identity: 25.4 N.A. N.A. 25.2 N.A. N.A.
Protein Similarity: 44 N.A. N.A. 42.7 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 14 0 7 7 60 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 20 0 0 0 0 7 0 0 14 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % D
% Glu: 0 0 7 0 0 0 0 0 0 7 0 0 7 0 0 % E
% Phe: 80 7 80 7 0 14 0 0 0 0 0 14 7 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 27 7 % H
% Ile: 0 0 0 0 47 0 0 0 7 0 7 7 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 7 7 0 0 0 0 7 0 % K
% Leu: 7 87 7 0 20 7 0 7 20 0 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 54 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 7 0 0 7 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 80 7 0 0 0 0 7 14 7 % P
% Gln: 0 0 0 7 7 0 0 0 0 0 7 7 7 7 0 % Q
% Arg: 7 0 0 0 0 0 0 34 0 14 0 0 7 0 0 % R
% Ser: 7 0 0 74 0 20 7 27 0 0 7 0 7 7 0 % S
% Thr: 0 7 0 7 0 7 0 0 0 0 14 0 54 7 87 % T
% Val: 0 0 0 0 20 7 0 0 0 0 60 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 7 7 14 7 0 7 0 67 0 14 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _