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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1609 All Species: 15.76
Human Site: S41 Identified Species: 24.76
UniProt: Q6P9B6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P9B6 NP_065998 456 51033 S41 D K N S P N V S S K S F S L K
Chimpanzee Pan troglodytes XP_511145 551 60941 S136 D K N S P N V S S K S F S L K
Rhesus Macaque Macaca mulatta XP_001110946 501 55814 S86 D K N S P N V S S K S F S L K
Dog Lupus familis XP_546801 511 57349 S97 E K H S S D T S P R S F S L K
Cat Felis silvestris
Mouse Mus musculus Q8K0P3 455 50826 A39 S S S E G G V A T G T F S L E
Rat Rattus norvegicus XP_226525 475 52815 A39 S S S D G G V A T G T F S L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509591 593 64379 K170 L D G S S G I K D G K T P Q K
Chicken Gallus gallus Q5ZJX5 468 52097 M46 A A K N G K A M K K T M T L E
Frog Xenopus laevis Q6DDZ9 460 52066 S41 M Q S G P K K S V G L Q Y F Q
Zebra Danio Brachydanio rerio Q1LWV7 450 49931 G41 A R S S A S A G K T S K G L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609110 448 51415 L42 E K L T Q D R L V E T W S Q T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502405 399 45748 H21 I N D E D Y A H F M E K L K K
Sea Urchin Strong. purpuratus XP_794130 468 51947 E42 E E L Q N V F E R I C Q S N Q
Poplar Tree Populus trichocarpa XP_002308447 422 46639 S41 S L A A Q S E S N N E Y I S L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196244 424 47406 N42 L A S N S Q S N D Q Y V S Y P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.1 86.2 70.2 N.A. 65.1 60.8 N.A. 49.5 58.9 48.2 43.6 N.A. 31.3 N.A. 27.1 39.3
Protein Similarity: 100 82.4 88.2 79 N.A. 79.6 74.7 N.A. 60.7 76.7 67.8 63.3 N.A. 52.8 N.A. 46.2 53.8
P-Site Identity: 100 100 100 53.3 N.A. 26.6 26.6 N.A. 13.3 13.3 13.3 20 N.A. 13.3 N.A. 6.6 6.6
P-Site Similarity: 100 100 100 80 N.A. 60 60 N.A. 20 40 33.3 40 N.A. 53.3 N.A. 13.3 26.6
Percent
Protein Identity: 25.4 N.A. N.A. 25.2 N.A. N.A.
Protein Similarity: 44 N.A. N.A. 42.7 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 14 7 7 7 0 20 14 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 20 7 7 7 7 14 0 0 14 0 0 0 0 0 0 % D
% Glu: 20 7 0 14 0 0 7 7 0 7 14 0 0 0 20 % E
% Phe: 0 0 0 0 0 0 7 0 7 0 0 40 0 7 0 % F
% Gly: 0 0 7 7 20 20 0 7 0 27 0 0 7 0 0 % G
% His: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 7 0 0 7 0 0 7 0 0 % I
% Lys: 0 34 7 0 0 14 7 7 14 27 7 14 0 7 40 % K
% Leu: 14 7 14 0 0 0 0 7 0 0 7 0 7 54 7 % L
% Met: 7 0 0 0 0 0 0 7 0 7 0 7 0 0 0 % M
% Asn: 0 7 20 14 7 20 0 7 7 7 0 0 0 7 0 % N
% Pro: 0 0 0 0 27 0 0 0 7 0 0 0 7 0 7 % P
% Gln: 0 7 0 7 14 7 0 0 0 7 0 14 0 14 14 % Q
% Arg: 0 7 0 0 0 0 7 0 7 7 0 0 0 0 0 % R
% Ser: 20 14 34 40 20 14 7 40 20 0 34 0 60 7 7 % S
% Thr: 0 0 0 7 0 0 7 0 14 7 27 7 7 0 7 % T
% Val: 0 0 0 0 0 7 34 0 14 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 7 7 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _