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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA1609
All Species:
33.64
Human Site:
S425
Identified Species:
52.86
UniProt:
Q6P9B6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P9B6
NP_065998
456
51033
S425
Q
L
A
K
G
N
K
S
I
L
D
A
D
P
E
Chimpanzee
Pan troglodytes
XP_511145
551
60941
S520
Q
L
A
K
G
N
K
S
I
L
D
A
D
P
E
Rhesus Macaque
Macaca mulatta
XP_001110946
501
55814
S470
Q
L
A
K
S
N
K
S
I
L
D
A
D
P
E
Dog
Lupus familis
XP_546801
511
57349
S480
Q
Q
A
K
S
S
R
S
V
L
D
K
N
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0P3
455
50826
S423
Y
E
G
K
N
K
K
S
V
L
D
S
N
P
E
Rat
Rattus norvegicus
XP_226525
475
52815
V423
D
Q
L
L
Q
G
V
V
S
W
E
I
H
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509591
593
64379
S559
E
V
N
K
G
K
K
S
I
L
D
A
D
P
E
Chicken
Gallus gallus
Q5ZJX5
468
52097
S433
A
E
T
K
G
K
K
S
I
L
D
V
D
P
E
Frog
Xenopus laevis
Q6DDZ9
460
52066
S427
L
L
A
K
N
P
R
S
I
L
D
S
D
T
E
Zebra Danio
Brachydanio rerio
Q1LWV7
450
49931
S418
E
E
D
E
K
K
K
S
I
L
D
A
D
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609110
448
51415
S417
E
G
D
G
H
K
R
S
V
L
D
G
N
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502405
399
45748
P371
K
S
I
I
D
K
D
P
E
A
R
A
V
L
E
Sea Urchin
Strong. purpuratus
XP_794130
468
51947
S420
D
E
E
G
G
H
K
S
I
L
D
K
D
A
A
Poplar Tree
Populus trichocarpa
XP_002308447
422
46639
L394
N
G
A
Q
Q
E
K
L
D
A
A
K
G
T
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196244
424
47406
H395
S
N
E
Q
D
T
K
H
N
A
M
K
G
T
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.1
86.2
70.2
N.A.
65.1
60.8
N.A.
49.5
58.9
48.2
43.6
N.A.
31.3
N.A.
27.1
39.3
Protein Similarity:
100
82.4
88.2
79
N.A.
79.6
74.7
N.A.
60.7
76.7
67.8
63.3
N.A.
52.8
N.A.
46.2
53.8
P-Site Identity:
100
100
93.3
53.3
N.A.
46.6
0
N.A.
73.3
66.6
60
53.3
N.A.
26.6
N.A.
13.3
46.6
P-Site Similarity:
100
100
93.3
80
N.A.
66.6
13.3
N.A.
86.6
66.6
73.3
66.6
N.A.
53.3
N.A.
20
53.3
Percent
Protein Identity:
25.4
N.A.
N.A.
25.2
N.A.
N.A.
Protein Similarity:
44
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
40
0
0
0
0
0
0
20
7
40
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
14
0
14
0
7
0
7
0
74
0
54
0
0
% D
% Glu:
20
27
14
7
0
7
0
0
7
0
7
0
0
0
74
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
7
14
34
7
0
0
0
0
0
7
14
0
0
% G
% His:
0
0
0
0
7
7
0
7
0
0
0
0
7
0
0
% H
% Ile:
0
0
7
7
0
0
0
0
54
0
0
7
0
0
0
% I
% Lys:
7
0
0
54
7
40
67
0
0
0
0
27
0
0
0
% K
% Leu:
7
27
7
7
0
0
0
7
0
74
0
0
0
27
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
7
7
0
14
20
0
0
7
0
0
0
20
0
0
% N
% Pro:
0
0
0
0
0
7
0
7
0
0
0
0
0
47
0
% P
% Gln:
27
14
0
14
14
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
20
0
0
0
7
0
0
0
0
% R
% Ser:
7
7
0
0
14
7
0
74
7
0
0
14
0
0
0
% S
% Thr:
0
0
7
0
0
7
0
0
0
0
0
0
0
20
0
% T
% Val:
0
7
0
0
0
0
7
7
20
0
0
7
7
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _