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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS5 All Species: 23.64
Human Site: S272 Identified Species: 57.78
UniProt: Q6P9B9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P9B9 NP_085131.1 1019 107995 S272 G S S S Q T P S T D P F P G S
Chimpanzee Pan troglodytes XP_001154137 1019 107952 S272 G S S S Q T P S T D P F P G S
Rhesus Macaque Macaca mulatta XP_001116423 1019 107905 S272 G S S S Q T P S T D P F P G S
Dog Lupus familis XP_855045 1019 107993 S272 G S S S Q T P S I D P F P G S
Cat Felis silvestris
Mouse Mus musculus Q8CHT3 1018 108329 S271 G N S S Q P P S T D P F P G S
Rat Rattus norvegicus NP_001101046 1019 108385 S272 G S S S Q T P S S D P F P G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693062 1023 111247 S262 Q Q A I D K S S R V P K I G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650303 994 112954 V292 Q S L V N V L V E I Y T E D M
Honey Bee Apis mellifera XP_397067 908 101831 L259 L F K V K I M L S V N W S L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785265 884 97917 I243 T S Q H S Q D I R K A L L D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.2 97.5 N.A. 95.2 95.2 N.A. N.A. N.A. N.A. 51.5 N.A. 22.2 28.4 N.A. 32.7
Protein Similarity: 100 99.9 99.5 98.4 N.A. 97.1 97 N.A. N.A. N.A. N.A. 65.1 N.A. 36.1 45.4 N.A. 48.9
P-Site Identity: 100 100 100 93.3 N.A. 86.6 93.3 N.A. N.A. N.A. N.A. 26.6 N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 100 N.A. N.A. N.A. N.A. 33.3 N.A. 6.6 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 10 0 0 60 0 0 0 20 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 10 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 60 0 0 0 % F
% Gly: 60 0 0 0 0 0 0 0 0 0 0 0 0 70 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 10 0 10 10 10 0 0 10 0 0 % I
% Lys: 0 0 10 0 10 10 0 0 0 10 0 10 0 0 0 % K
% Leu: 10 0 10 0 0 0 10 10 0 0 0 10 10 10 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % M
% Asn: 0 10 0 0 10 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 60 0 0 0 70 0 60 0 0 % P
% Gln: 20 10 10 0 60 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % R
% Ser: 0 70 60 60 10 0 10 70 20 0 0 0 10 0 70 % S
% Thr: 10 0 0 0 0 50 0 0 40 0 0 10 0 0 0 % T
% Val: 0 0 0 20 0 10 0 10 0 20 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _