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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS5
All Species:
25.45
Human Site:
S727
Identified Species:
62.22
UniProt:
Q6P9B9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P9B9
NP_085131.1
1019
107995
S727
S
A
S
L
A
S
A
S
L
L
D
T
N
R
R
Chimpanzee
Pan troglodytes
XP_001154137
1019
107952
S727
S
A
S
L
A
S
A
S
L
L
D
T
N
R
R
Rhesus Macaque
Macaca mulatta
XP_001116423
1019
107905
S727
S
A
S
L
A
S
A
S
L
L
D
T
N
R
R
Dog
Lupus familis
XP_855045
1019
107993
S727
S
A
P
L
A
S
A
S
L
L
D
T
N
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHT3
1018
108329
S726
S
T
P
L
A
S
A
S
L
L
D
I
N
R
R
Rat
Rattus norvegicus
NP_001101046
1019
108385
S727
S
T
P
L
A
S
A
S
L
L
D
I
N
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693062
1023
111247
S734
L
V
P
D
L
G
I
S
L
L
D
V
N
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650303
994
112954
S712
L
Q
N
L
H
T
S
S
G
A
N
S
N
R
S
Honey Bee
Apis mellifera
XP_397067
908
101831
N649
E
I
L
L
L
H
Q
N
H
K
Q
V
T
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785265
884
97917
K628
A
V
S
D
I
E
T
K
Q
T
N
S
R
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.2
97.5
N.A.
95.2
95.2
N.A.
N.A.
N.A.
N.A.
51.5
N.A.
22.2
28.4
N.A.
32.7
Protein Similarity:
100
99.9
99.5
98.4
N.A.
97.1
97
N.A.
N.A.
N.A.
N.A.
65.1
N.A.
36.1
45.4
N.A.
48.9
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
40
N.A.
26.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
60
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
40
0
0
60
0
60
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
0
0
0
0
0
70
0
0
0
0
% D
% Glu:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
10
0
0
0
0
20
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
10
% K
% Leu:
20
0
10
80
20
0
0
0
70
70
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
0
0
20
0
80
0
0
% N
% Pro:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
10
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
80
60
% R
% Ser:
60
0
40
0
0
60
10
80
0
0
0
20
0
10
10
% S
% Thr:
0
20
0
0
0
10
10
0
0
10
0
40
10
0
10
% T
% Val:
0
20
0
0
0
0
0
0
0
0
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _