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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC8B
All Species:
17.27
Human Site:
Y683
Identified Species:
47.5
UniProt:
Q6P9F7
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P9F7
NP_001127948.1
803
92390
Y683
F
L
C
T
K
L
H
Y
L
D
L
S
Y
N
H
Chimpanzee
Pan troglodytes
XP_001150203
803
92370
Y683
F
L
C
T
K
L
H
Y
L
D
L
S
Y
N
H
Rhesus Macaque
Macaca mulatta
XP_001109419
754
87489
C643
Q
H
L
H
R
L
T
C
L
K
L
W
Y
N
H
Dog
Lupus familis
XP_537083
803
92293
Y683
F
L
C
T
K
L
H
Y
L
D
L
S
Y
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU41
791
90870
Y671
F
L
C
T
K
L
H
Y
L
D
L
S
Y
N
H
Rat
Rattus norvegicus
Q4V8I7
810
94143
Y689
F
Y
C
R
K
L
R
Y
L
D
L
S
H
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507038
801
91849
H681
F
L
C
T
K
L
Y
H
L
D
L
S
S
N
N
Chicken
Gallus gallus
Q5F4C4
529
59144
V421
L
T
K
I
P
E
D
V
S
G
L
V
S
L
E
Frog
Xenopus laevis
Q6NU09
806
92226
H690
F
L
C
N
K
L
R
H
L
D
L
S
F
N
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
54
96.8
N.A.
92.1
58.2
N.A.
88.5
20.7
47.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
71.4
99
N.A.
95.8
75.8
N.A.
94.4
36.1
67.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
40
100
N.A.
100
66.6
N.A.
73.3
6.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
100
N.A.
100
80
N.A.
93.3
6.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
78
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
78
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
23
% E
% Phe:
78
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
12
0
12
0
0
45
23
0
0
0
0
12
0
56
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
78
0
0
0
0
12
0
0
0
0
0
% K
% Leu:
12
67
12
0
0
89
0
0
89
0
100
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
0
0
89
23
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
12
0
23
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
12
0
0
78
23
0
0
% S
% Thr:
0
12
0
56
0
0
12
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
12
0
0
0
0
12
56
0
0
0
0
56
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _