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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5D1 All Species: 6.06
Human Site: Y125 Identified Species: 14.81
UniProt: Q6P9G0 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P9G0 NP_653208.2 228 26689 Y125 K P W W Q G S Y Y E V G R L S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110765 228 26654 Y125 K P W W Q G S Y Y E V G R L S
Dog Lupus familis XP_849932 235 27421 R132 K P W W Q G T R Y E V G R L S
Cat Felis silvestris
Mouse Mus musculus Q5NCY3 228 26701 N125 V P W W K G A N Y Q V G R L S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517698 409 45928 R306 R P W W E G T R Y Q V G L L A
Chicken Gallus gallus
Frog Xenopus laevis Q5PPR6 217 25222 Y115 P W W K D T I Y Q V G I L S S
Zebra Danio Brachydanio rerio Q567I9 214 24878 R112 K P W W K D N R Y E V G L L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122568 230 26694 W127 A L D K C P W W L D E K Y K I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203384 214 24990 Y112 P W W K D E G Y C I G I L S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9P5L0 139 14595 E36 D I T K F V D E H P G G E E V
Conservation
Percent
Protein Identity: 100 N.A. 98.6 85.5 N.A. 83.3 N.A. N.A. 38.3 N.A. 61.4 64.9 N.A. N.A. 39.1 N.A. 59.2
Protein Similarity: 100 N.A. 100 91.4 N.A. 93.4 N.A. N.A. 46.4 N.A. 76.7 75.4 N.A. N.A. 56 N.A. 73.2
P-Site Identity: 100 N.A. 100 86.6 N.A. 66.6 N.A. N.A. 53.3 N.A. 20 66.6 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 N.A. 100 93.3 N.A. 86.6 N.A. N.A. 86.6 N.A. 20 80 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.1
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 30.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 20 10 10 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 10 0 10 0 40 10 0 10 10 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 50 10 0 0 0 30 70 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 10 0 0 10 0 20 0 0 10 % I
% Lys: 40 0 0 40 20 0 0 0 0 0 0 10 0 10 10 % K
% Leu: 0 10 0 0 0 0 0 0 10 0 0 0 40 60 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % N
% Pro: 20 60 0 0 0 10 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 30 0 0 0 10 20 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 30 0 0 0 0 40 0 0 % R
% Ser: 0 0 0 0 0 0 20 0 0 0 0 0 0 20 60 % S
% Thr: 0 0 10 0 0 10 20 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 10 0 0 0 10 60 0 0 0 10 % V
% Trp: 0 20 80 60 0 0 10 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 40 60 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _