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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNKSR3
All Species:
27.58
Human Site:
S477
Identified Species:
60.67
UniProt:
Q6P9H4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P9H4
NP_775786.2
555
61904
S477
I
P
P
I
I
E
E
S
S
S
P
P
Y
R
F
Chimpanzee
Pan troglodytes
XP_518820
565
63028
S487
I
P
P
I
I
E
E
S
S
S
P
P
Y
R
F
Rhesus Macaque
Macaca mulatta
XP_001095122
555
61944
S477
I
P
P
I
V
E
E
S
S
S
H
P
Y
R
F
Dog
Lupus familis
XP_541159
1069
118701
S584
I
P
P
I
I
E
E
S
S
S
A
P
Y
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMA3
555
61851
S477
I
T
P
I
T
E
E
S
A
S
P
M
Y
R
F
Rat
Rattus norvegicus
Q5SGD7
555
61832
S477
I
T
P
I
I
E
E
S
A
S
P
V
Y
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510657
574
64138
S496
I
P
P
I
I
E
E
S
F
S
S
Q
H
R
F
Chicken
Gallus gallus
XP_419685
653
70864
S575
I
P
P
I
I
E
E
S
P
S
T
Q
H
P
F
Frog
Xenopus laevis
NP_001085442
981
110674
D892
S
F
I
K
R
S
S
D
P
V
V
N
D
K
L
Zebra Danio
Brachydanio rerio
NP_001107119
546
60785
E469
Q
I
P
T
I
S
E
E
S
P
C
Y
P
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800096
1143
125961
N1023
S
M
S
S
I
N
T
N
S
T
T
T
S
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
98.9
49.2
N.A.
92.2
92.4
N.A.
83.9
73.3
30.6
63.5
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
100
96.6
99.4
50.3
N.A.
95.3
94.7
N.A.
87.4
77.7
41.6
78.1
N.A.
N.A.
N.A.
N.A.
31.5
P-Site Identity:
100
100
86.6
93.3
N.A.
73.3
80
N.A.
73.3
66.6
0
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
86.6
N.A.
80
73.3
6.6
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
19
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
73
82
10
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
73
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
19
0
10
% H
% Ile:
73
10
10
73
73
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% N
% Pro:
0
55
82
0
0
0
0
0
19
10
37
37
10
10
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
64
0
% R
% Ser:
19
0
10
10
0
19
10
73
55
73
10
0
10
0
0
% S
% Thr:
0
19
0
10
10
0
10
0
0
10
19
10
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
0
10
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
55
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _