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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNKSR3 All Species: 29.09
Human Site: S537 Identified Species: 64
UniProt: Q6P9H4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P9H4 NP_775786.2 555 61904 S537 S S A T K S S S T E P S L L V
Chimpanzee Pan troglodytes XP_518820 565 63028 S547 S S A T K S S S A E P S L L V
Rhesus Macaque Macaca mulatta XP_001095122 555 61944 S537 S S A T K S S S T E P S L L V
Dog Lupus familis XP_541159 1069 118701 S644 S S S A A K A S T E P S L L V
Cat Felis silvestris
Mouse Mus musculus Q8BMA3 555 61851 S537 S S S A K A S S G E P S L L V
Rat Rattus norvegicus Q5SGD7 555 61832 S537 S S S A K A S S G E P S L L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510657 574 64138 S556 R S S P K S S S A E P S L F V
Chicken Gallus gallus XP_419685 653 70864 S635 T S S T K S S S A E P S L L V
Frog Xenopus laevis NP_001085442 981 110674 N952 L D I C Q K S N S K D V E S V
Zebra Danio Brachydanio rerio NP_001107119 546 60785 S529 K S S K R P P S E P S V F S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800096 1143 125961 H1083 T D L S G S T H L S P E R L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.5 98.9 49.2 N.A. 92.2 92.4 N.A. 83.9 73.3 30.6 63.5 N.A. N.A. N.A. N.A. 20.1
Protein Similarity: 100 96.6 99.4 50.3 N.A. 95.3 94.7 N.A. 87.4 77.7 41.6 78.1 N.A. N.A. N.A. N.A. 31.5
P-Site Identity: 100 93.3 100 66.6 N.A. 73.3 73.3 N.A. 66.6 80 13.3 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 93.3 100 80 N.A. 86.6 86.6 N.A. 73.3 93.3 40 26.6 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 28 28 10 19 10 0 28 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 0 0 0 0 0 0 0 10 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 10 73 0 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % F
% Gly: 0 0 0 0 10 0 0 0 19 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 10 64 19 0 0 0 10 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 0 0 0 10 0 0 0 73 73 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 10 10 0 0 10 82 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 55 82 55 10 0 55 73 82 10 10 10 73 0 19 10 % S
% Thr: 19 0 0 37 0 0 10 0 28 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 82 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _