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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNKSR3
All Species:
30.61
Human Site:
Y464
Identified Species:
67.33
UniProt:
Q6P9H4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P9H4
NP_775786.2
555
61904
Y464
G
E
D
A
L
C
R
Y
F
S
N
E
R
I
P
Chimpanzee
Pan troglodytes
XP_518820
565
63028
Y474
G
E
D
A
L
C
R
Y
F
S
N
E
R
I
P
Rhesus Macaque
Macaca mulatta
XP_001095122
555
61944
Y464
G
E
D
A
L
C
R
Y
F
S
N
E
R
I
P
Dog
Lupus familis
XP_541159
1069
118701
Y571
G
E
D
A
L
C
R
Y
F
S
N
E
R
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMA3
555
61851
Y464
G
E
D
A
L
C
R
Y
F
S
N
E
R
I
T
Rat
Rattus norvegicus
Q5SGD7
555
61832
Y464
G
E
D
A
L
C
R
Y
F
S
N
E
R
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510657
574
64138
Y483
G
D
D
V
L
C
R
Y
F
S
N
E
R
I
P
Chicken
Gallus gallus
XP_419685
653
70864
Y562
G
E
D
V
L
C
R
Y
F
S
N
E
R
I
P
Frog
Xenopus laevis
NP_001085442
981
110674
K879
G
D
R
R
L
S
T
K
V
E
Y
K
K
S
F
Zebra Danio
Brachydanio rerio
NP_001107119
546
60785
R456
K
G
D
E
L
L
H
R
Y
L
S
N
E
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800096
1143
125961
D1010
S
D
P
D
S
T
T
D
M
A
L
S
S
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
98.9
49.2
N.A.
92.2
92.4
N.A.
83.9
73.3
30.6
63.5
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
100
96.6
99.4
50.3
N.A.
95.3
94.7
N.A.
87.4
77.7
41.6
78.1
N.A.
N.A.
N.A.
N.A.
31.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
93.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
33.3
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
55
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
73
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
28
82
10
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
64
0
10
0
0
0
0
0
10
0
73
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
10
% F
% Gly:
82
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
73
10
% I
% Lys:
10
0
0
0
0
0
0
10
0
0
0
10
10
0
0
% K
% Leu:
0
0
0
0
91
10
0
0
0
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
73
10
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
55
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
10
10
0
0
73
10
0
0
0
0
73
0
0
% R
% Ser:
10
0
0
0
10
10
0
0
0
73
10
10
10
19
0
% S
% Thr:
0
0
0
0
0
10
19
0
0
0
0
0
0
0
19
% T
% Val:
0
0
0
19
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _