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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFWD3
All Species:
4.55
Human Site:
T677
Identified Species:
14.29
UniProt:
Q6PCD5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PCD5
NP_060594.3
774
85094
T677
M
S
Y
R
L
D
D
T
G
N
P
I
C
S
C
Chimpanzee
Pan troglodytes
XP_001137255
774
85068
T677
M
S
Y
R
L
D
D
T
G
N
P
I
C
S
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853024
773
85269
A676
M
S
Y
K
L
D
D
A
G
E
P
V
C
I
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIK8
774
84294
A677
M
S
Y
K
L
D
D
A
G
E
P
V
C
S
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514261
744
80102
N649
Y
I
P
D
S
A
G
N
P
I
C
S
C
Q
P
Chicken
Gallus gallus
XP_414051
670
73089
D575
P
L
T
E
A
S
E
D
V
V
C
S
S
N
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393432
491
55412
K396
H
I
V
C
T
I
E
K
G
N
D
E
S
T
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326378
681
75875
A586
S
H
L
H
L
K
R
A
G
S
N
Y
E
K
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
77.1
N.A.
68.2
N.A.
N.A.
57.3
53.2
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
Protein Similarity:
100
99.4
N.A.
86.3
N.A.
79
N.A.
N.A.
70
65.2
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
N.A.
P-Site Identity:
100
100
N.A.
66.6
N.A.
73.3
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
80
N.A.
86.6
N.A.
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
24
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
13
0
38
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
13
0
0
0
0
0
0
25
0
63
0
50
% C
% Asp:
0
0
0
13
0
50
50
13
0
0
13
0
0
0
0
% D
% Glu:
0
0
0
13
0
0
25
0
0
25
0
13
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
13
0
75
0
0
0
0
0
0
% G
% His:
13
13
0
13
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
0
0
13
0
0
0
13
0
25
0
13
13
% I
% Lys:
0
0
0
25
0
13
0
13
0
0
0
0
0
13
0
% K
% Leu:
0
13
13
0
63
0
0
0
0
0
0
0
0
0
13
% L
% Met:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
38
13
0
0
13
0
% N
% Pro:
13
0
13
0
0
0
0
0
13
0
50
0
0
0
25
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
0
0
0
25
0
0
13
0
0
0
0
0
0
0
0
% R
% Ser:
13
50
0
0
13
13
0
0
0
13
0
25
25
38
0
% S
% Thr:
0
0
13
0
13
0
0
25
0
0
0
0
0
13
0
% T
% Val:
0
0
13
0
0
0
0
0
13
13
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
50
0
0
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _