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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXL19 All Species: 25.15
Human Site: S388 Identified Species: 61.48
UniProt: Q6PCT2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PCT2 NP_001093254.2 674 73771 S388 V V R P P P R S P E P D T L P
Chimpanzee Pan troglodytes XP_510938 554 61242 H295 A W L R V F Q H L G P R E L C
Rhesus Macaque Macaca mulatta XP_001111440 674 73752 S388 V V R P P P R S P E P D T L P
Dog Lupus familis XP_849040 690 75269 S404 V V R P P P R S P E P D T L P
Cat Felis silvestris
Mouse Mus musculus Q6PB97 674 73769 S388 V V R P P P R S P E P D T L P
Rat Rattus norvegicus NP_001101022 504 55818 H264 R P P Q L E R H V V R P P P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415137 1259 144624 S972 V I R P P P I S P P P D S L P
Frog Xenopus laevis Q640I9 1259 144035 S972 V I R P P P I S P P P D S L P
Zebra Danio Brachydanio rerio XP_708792 1213 137462 S926 V I R P P P I S P P P D R L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHH9 1345 146160 G1040 G A G N G E R G T N N G G L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.6 100 91.3 N.A. 97.4 74 N.A. N.A. 28.2 27.3 27.9 N.A. 20.5 N.A. N.A. N.A.
Protein Similarity: 100 72.4 100 91.3 N.A. 98.9 74.6 N.A. N.A. 37.7 36.6 38.1 N.A. 30.1 N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 100 N.A. 100 6.6 N.A. N.A. 73.3 73.3 73.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 6.6 N.A. N.A. 86.6 86.6 80 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 % D
% Glu: 0 0 0 0 0 20 0 0 0 40 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 10 0 0 10 0 10 0 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % H
% Ile: 0 30 0 0 0 0 30 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 10 0 0 0 10 0 0 0 0 90 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 10 10 0 0 0 0 % N
% Pro: 0 10 10 70 70 70 0 0 70 30 80 10 10 10 70 % P
% Gln: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 70 10 0 0 60 0 0 0 10 10 10 0 10 % R
% Ser: 0 0 0 0 0 0 0 70 0 0 0 0 20 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 40 0 0 % T
% Val: 70 40 0 0 10 0 0 0 10 10 0 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _