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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL19
All Species:
25.15
Human Site:
S388
Identified Species:
61.48
UniProt:
Q6PCT2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PCT2
NP_001093254.2
674
73771
S388
V
V
R
P
P
P
R
S
P
E
P
D
T
L
P
Chimpanzee
Pan troglodytes
XP_510938
554
61242
H295
A
W
L
R
V
F
Q
H
L
G
P
R
E
L
C
Rhesus Macaque
Macaca mulatta
XP_001111440
674
73752
S388
V
V
R
P
P
P
R
S
P
E
P
D
T
L
P
Dog
Lupus familis
XP_849040
690
75269
S404
V
V
R
P
P
P
R
S
P
E
P
D
T
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6PB97
674
73769
S388
V
V
R
P
P
P
R
S
P
E
P
D
T
L
P
Rat
Rattus norvegicus
NP_001101022
504
55818
H264
R
P
P
Q
L
E
R
H
V
V
R
P
P
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415137
1259
144624
S972
V
I
R
P
P
P
I
S
P
P
P
D
S
L
P
Frog
Xenopus laevis
Q640I9
1259
144035
S972
V
I
R
P
P
P
I
S
P
P
P
D
S
L
P
Zebra Danio
Brachydanio rerio
XP_708792
1213
137462
S926
V
I
R
P
P
P
I
S
P
P
P
D
R
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHH9
1345
146160
G1040
G
A
G
N
G
E
R
G
T
N
N
G
G
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.6
100
91.3
N.A.
97.4
74
N.A.
N.A.
28.2
27.3
27.9
N.A.
20.5
N.A.
N.A.
N.A.
Protein Similarity:
100
72.4
100
91.3
N.A.
98.9
74.6
N.A.
N.A.
37.7
36.6
38.1
N.A.
30.1
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
N.A.
73.3
73.3
73.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
6.6
N.A.
N.A.
86.6
86.6
80
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% D
% Glu:
0
0
0
0
0
20
0
0
0
40
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
10
0
0
10
0
10
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% H
% Ile:
0
30
0
0
0
0
30
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
10
0
0
0
10
0
0
0
0
90
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
10
10
70
70
70
0
0
70
30
80
10
10
10
70
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
70
10
0
0
60
0
0
0
10
10
10
0
10
% R
% Ser:
0
0
0
0
0
0
0
70
0
0
0
0
20
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
40
0
0
% T
% Val:
70
40
0
0
10
0
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _