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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM88 All Species: 20.3
Human Site: S74 Identified Species: 63.81
UniProt: Q6PEY1 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PEY1 NP_981956.1 159 17251 S74 C H S Q F L R S Q A P P C T A
Chimpanzee Pan troglodytes XP_001174852 159 17212 S74 C H S Q F L R S Q A P P C T A
Rhesus Macaque Macaca mulatta XP_001110648 159 17143 S74 C H S Q F L R S Q A P P C T A
Dog Lupus familis XP_849909 159 17191 S74 C H S Q F L R S Q A P P C T A
Cat Felis silvestris
Mouse Mus musculus Q9D0N8 159 17339 S74 C H S Q F L R S Q A P L C T S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517691 162 17422 A71 C H S Q F L H A Q V P P C T K
Chicken Gallus gallus XP_417575 179 20239 S94 C H S R V L H S T A R Y C R T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_991233 215 22448 G127 H S T V Q R H G T S L Y C S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.5 97.4 92.4 N.A. 88.6 N.A. N.A. 69.1 34.6 N.A. 39 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 93 97.4 94.9 N.A. 92.4 N.A. N.A. 79 53 N.A. 49.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 N.A. N.A. 73.3 46.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 80 53.3 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 13 0 75 0 0 0 0 50 % A
% Cys: 88 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % G
% His: 13 88 0 0 0 0 38 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % K
% Leu: 0 0 0 0 0 88 0 0 0 0 13 13 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 75 63 0 0 0 % P
% Gln: 0 0 0 75 13 0 0 0 75 0 0 0 0 0 0 % Q
% Arg: 0 0 0 13 0 13 63 0 0 0 13 0 0 13 0 % R
% Ser: 0 13 88 0 0 0 0 75 0 13 0 0 0 13 13 % S
% Thr: 0 0 13 0 0 0 0 0 25 0 0 0 0 75 13 % T
% Val: 0 0 0 13 13 0 0 0 0 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _