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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
16.97
Human Site:
S1007
Identified Species:
31.11
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
S1007
G
G
Y
R
L
F
S
S
S
R
P
P
T
E
M
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
M984
R
N
R
K
A
G
S
M
E
V
L
S
E
T
S
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
L832
S
E
S
H
V
H
S
L
L
S
I
L
R
Y
G
Dog
Lupus familis
XP_535450
1457
162086
S1003
G
S
Y
R
L
F
S
S
A
R
P
P
T
E
M
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
S1002
G
G
Y
R
L
F
S
S
S
R
P
P
T
E
M
Rat
Rattus norvegicus
P0C644
1434
159600
S1004
G
G
Y
R
L
F
S
S
S
R
P
P
T
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
M874
P
L
Y
S
R
G
V
M
S
P
E
R
H
V
R
Chicken
Gallus gallus
XP_413955
1359
152194
S945
Q
G
S
L
E
D
L
S
K
E
K
G
M
D
E
Frog
Xenopus laevis
Q5XHF8
1131
128702
K720
L
M
L
R
R
W
S
K
L
E
K
D
F
K
T
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
S937
G
F
G
F
R
P
A
S
A
E
N
D
Q
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
I1023
F
K
S
K
P
I
P
I
G
A
H
H
T
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
L912
P
R
F
H
I
E
I
L
F
S
P
G
L
Y
P
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
S922
S
E
E
D
E
P
S
S
C
I
D
S
S
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
6.6
6.6
86.6
N.A.
100
100
N.A.
13.3
13.3
13.3
13.3
N.A.
6.6
N.A.
6.6
20
P-Site Similarity:
100
13.3
13.3
93.3
N.A.
100
100
N.A.
13.3
20
26.6
33.3
N.A.
13.3
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
16
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
0
0
0
8
16
0
8
8
% D
% Glu:
0
16
8
0
16
8
0
0
8
24
8
0
8
39
8
% E
% Phe:
8
8
8
8
0
31
0
0
8
0
0
0
8
0
0
% F
% Gly:
39
31
8
0
0
16
0
0
8
0
0
16
0
0
8
% G
% His:
0
0
0
16
0
8
0
0
0
0
8
8
8
0
0
% H
% Ile:
0
0
0
0
8
8
8
8
0
8
8
0
0
0
0
% I
% Lys:
0
8
0
16
0
0
0
8
8
0
16
0
0
16
0
% K
% Leu:
8
8
8
8
31
0
8
16
16
0
8
8
8
0
0
% L
% Met:
0
8
0
0
0
0
0
16
0
0
0
0
8
0
31
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
16
0
0
0
8
16
8
0
0
8
39
31
0
0
8
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
8
8
8
39
24
0
0
0
0
31
0
8
8
0
8
% R
% Ser:
16
8
24
8
0
0
62
54
31
16
0
16
8
0
16
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
39
8
8
% T
% Val:
0
0
0
0
8
0
8
0
0
8
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
39
0
0
0
0
0
0
0
0
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _