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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
6.67
Human Site:
S1137
Identified Species:
12.22
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
S1137
L
F
D
S
M
H
S
S
Q
A
S
D
N
P
F
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
S1112
L
F
D
S
M
H
S
S
Q
A
S
D
N
P
F
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
R960
S
E
P
I
H
I
H
R
K
S
P
L
P
R
S
Dog
Lupus familis
XP_535450
1457
162086
Q1134
S
P
T
L
Q
L
R
Q
R
S
E
K
P
P
W
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
H1132
L
F
D
S
M
H
N
H
Q
A
S
D
S
P
F
Rat
Rattus norvegicus
P0C644
1434
159600
H1134
L
F
D
S
M
H
N
H
Q
A
S
D
N
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
K1002
D
E
E
P
H
A
S
K
R
D
E
P
D
R
A
Chicken
Gallus gallus
XP_413955
1359
152194
N1073
Y
P
L
E
T
L
H
N
S
L
S
L
R
Q
V
Frog
Xenopus laevis
Q5XHF8
1131
128702
S848
S
H
V
H
S
L
L
S
I
L
R
F
G
A
L
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
V1067
E
L
L
S
M
P
A
V
K
R
F
S
V
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
L1220
R
G
F
S
K
N
T
L
P
A
V
S
S
M
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
T1040
A
L
D
E
L
N
N
T
T
K
A
M
A
D
D
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
W1050
P
E
L
H
D
P
N
W
Y
F
N
D
D
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
100
0
6.6
N.A.
80
86.6
N.A.
6.6
6.6
6.6
20
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
13.3
26.6
N.A.
93.3
93.3
N.A.
26.6
13.3
6.6
33.3
N.A.
33.3
N.A.
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
8
0
0
39
8
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
39
0
8
0
0
0
0
8
0
39
16
8
8
% D
% Glu:
8
24
8
16
0
0
0
0
0
0
16
0
0
0
0
% E
% Phe:
0
31
8
0
0
0
0
0
0
8
8
8
0
0
39
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
8
0
16
16
31
16
16
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
8
16
8
0
8
0
0
0
% K
% Leu:
31
16
24
8
8
24
8
8
0
16
0
16
0
0
16
% L
% Met:
0
0
0
0
39
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
0
16
31
8
0
0
8
0
24
0
0
% N
% Pro:
8
16
8
8
0
16
0
0
8
0
8
8
16
39
0
% P
% Gln:
0
0
0
0
8
0
0
8
31
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
0
0
8
8
16
8
8
0
8
16
0
% R
% Ser:
24
0
0
47
8
0
24
24
8
16
39
16
16
8
8
% S
% Thr:
0
0
8
0
8
0
8
8
8
0
0
0
0
0
8
% T
% Val:
0
0
8
0
0
0
0
8
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _