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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
7.88
Human Site:
S1255
Identified Species:
14.44
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
S1255
S
Q
P
Y
E
E
V
S
Q
P
C
Q
E
V
P
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
S1230
S
Q
P
Y
E
E
V
S
Q
P
C
Q
E
V
P
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
L1078
G
S
S
S
A
P
N
L
Q
D
Y
A
R
T
H
Dog
Lupus familis
XP_535450
1457
162086
S1252
Q
D
I
P
E
E
V
S
Q
P
C
Q
E
V
P
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
V1250
C
P
S
G
S
Q
G
V
T
K
V
S
Q
T
C
Rat
Rattus norvegicus
P0C644
1434
159600
N1252
S
Q
D
D
T
E
V
N
Q
T
C
Q
E
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
L1120
V
E
Q
K
Q
N
A
L
G
T
H
C
A
G
L
Chicken
Gallus gallus
XP_413955
1359
152194
R1191
Q
S
P
E
Q
E
E
R
Q
P
D
S
G
G
L
Frog
Xenopus laevis
Q5XHF8
1131
128702
P966
R
A
L
V
M
F
K
P
M
V
S
D
P
I
H
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
P1185
P
T
T
A
D
T
S
P
R
F
S
F
S
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
M1338
G
I
A
S
I
Q
P
M
N
R
D
S
D
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
R1158
E
A
S
E
R
Q
S
R
S
R
R
Y
F
P
Y
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
A1168
P
S
P
T
E
S
S
A
K
N
F
D
F
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
100
6.6
73.3
N.A.
0
66.6
N.A.
0
26.6
0
0
N.A.
0
N.A.
0
13.3
P-Site Similarity:
100
100
6.6
73.3
N.A.
13.3
73.3
N.A.
13.3
33.3
6.6
13.3
N.A.
13.3
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
8
8
0
8
8
0
0
0
8
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
31
8
0
0
8
% C
% Asp:
0
8
8
8
8
0
0
0
0
8
16
16
8
0
0
% D
% Glu:
8
8
0
16
31
39
8
0
0
0
0
0
31
16
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
8
8
16
0
0
% F
% Gly:
16
0
0
8
0
0
8
0
8
0
0
0
8
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
16
% H
% Ile:
0
8
8
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
8
0
0
8
0
8
8
0
0
0
0
8
% K
% Leu:
0
0
8
0
0
0
0
16
0
0
0
0
0
0
24
% L
% Met:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
8
8
8
0
0
0
0
0
% N
% Pro:
16
8
31
8
0
8
8
16
0
31
0
0
8
8
31
% P
% Gln:
16
24
8
0
16
24
0
0
47
0
0
31
8
0
0
% Q
% Arg:
8
0
0
0
8
0
0
16
8
16
8
0
8
0
0
% R
% Ser:
24
24
24
16
8
8
24
24
8
0
16
24
8
8
0
% S
% Thr:
0
8
8
8
8
8
0
0
8
16
0
0
0
16
8
% T
% Val:
8
0
0
8
0
0
31
8
0
8
8
0
0
31
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
0
0
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _