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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
5.15
Human Site:
S1265
Identified Species:
9.44
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
S1265
C
Q
E
V
P
D
I
S
Q
P
C
Q
D
I
S
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
S1240
C
Q
E
V
P
D
I
S
Q
P
C
Q
D
I
S
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
K1088
Y
A
R
T
H
R
K
K
L
T
S
S
G
C
I
Dog
Lupus familis
XP_535450
1457
162086
G1262
C
Q
E
V
P
D
I
G
Q
P
C
Q
E
N
H
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
V1260
V
S
Q
T
C
Q
E
V
P
D
I
V
Q
P
C
Rat
Rattus norvegicus
P0C644
1434
159600
I1262
C
Q
E
V
P
D
T
I
Q
P
C
H
D
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
T1130
H
C
A
G
L
F
S
T
S
V
L
G
G
S
S
Chicken
Gallus gallus
XP_413955
1359
152194
E1201
D
S
G
G
L
G
G
E
V
G
M
S
G
L
P
Frog
Xenopus laevis
Q5XHF8
1131
128702
R976
S
D
P
I
H
I
H
R
K
S
P
L
P
R
S
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
L1195
S
F
S
E
K
I
T
L
T
P
Q
S
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
G1348
D
S
D
E
T
M
G
G
G
V
F
L
S
V
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
K1168
R
Y
F
P
Y
R
F
K
H
H
T
A
Q
L
L
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
E1178
F
D
F
S
L
F
L
E
S
M
K
S
Q
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
100
0
73.3
N.A.
0
73.3
N.A.
6.6
0
6.6
6.6
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
0
80
N.A.
6.6
73.3
N.A.
13.3
6.6
20
6.6
N.A.
13.3
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
31
8
0
0
8
0
0
0
0
0
31
0
0
8
16
% C
% Asp:
16
16
8
0
0
31
0
0
0
8
0
0
24
0
0
% D
% Glu:
0
0
31
16
0
0
8
16
0
0
0
0
8
8
8
% E
% Phe:
8
8
16
0
0
16
8
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
8
16
0
8
16
16
8
8
0
8
24
0
0
% G
% His:
8
0
0
0
16
0
8
0
8
8
0
8
0
0
8
% H
% Ile:
0
0
0
8
0
16
24
8
0
0
8
0
0
24
8
% I
% Lys:
0
0
0
0
8
0
8
16
8
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
24
0
8
8
8
0
8
16
0
16
16
% L
% Met:
0
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
8
8
31
0
0
0
8
39
8
0
8
8
8
% P
% Gln:
0
31
8
0
0
8
0
0
31
0
8
24
24
0
0
% Q
% Arg:
8
0
8
0
0
16
0
8
0
0
0
0
0
16
0
% R
% Ser:
16
24
8
8
0
0
8
16
16
8
8
31
16
8
31
% S
% Thr:
0
0
0
16
8
0
16
8
8
8
8
0
0
0
0
% T
% Val:
8
0
0
31
0
0
0
8
8
16
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _