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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
5.76
Human Site:
S1314
Identified Species:
10.56
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
S1314
S
Q
P
C
Q
K
S
S
Q
L
C
Q
K
V
S
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
S1289
S
Q
P
C
Q
K
S
S
Q
L
C
Q
K
V
S
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
A1137
P
L
E
T
L
H
N
A
L
S
L
K
Q
V
D
Dog
Lupus familis
XP_535450
1457
162086
V1311
C
Q
K
N
P
E
K
V
S
Q
P
S
L
D
V
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
Q1309
C
Q
A
S
Q
L
S
Q
K
V
C
E
E
I
C
Rat
Rattus norvegicus
P0C644
1434
159600
E1311
Q
L
S
K
K
V
Y
E
E
I
C
Q
L
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
N1179
C
P
L
E
T
L
H
N
A
L
S
L
K
Q
V
Chicken
Gallus gallus
XP_413955
1359
152194
V1250
N
P
K
E
K
R
M
V
E
L
E
E
D
S
A
Frog
Xenopus laevis
Q5XHF8
1131
128702
P1025
S
M
V
P
S
I
C
P
L
E
T
L
H
N
S
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
T1244
M
E
R
P
S
Q
I
T
S
D
G
T
D
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
D1397
E
G
F
D
D
D
E
D
A
T
L
S
A
A
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
A1217
K
D
F
G
A
G
T
A
V
L
S
T
A
V
I
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
D1227
M
S
M
P
S
L
D
D
D
L
V
I
G
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
100
6.6
6.6
N.A.
26.6
13.3
N.A.
13.3
6.6
13.3
0
N.A.
0
N.A.
13.3
6.6
P-Site Similarity:
100
100
33.3
13.3
N.A.
60
33.3
N.A.
20
46.6
13.3
26.6
N.A.
6.6
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
16
16
0
0
0
16
8
16
% A
% Cys:
24
0
0
16
0
0
8
0
0
0
31
0
0
8
8
% C
% Asp:
0
8
0
8
8
8
8
16
8
8
0
0
16
8
8
% D
% Glu:
8
8
8
16
0
8
8
8
16
8
8
16
8
0
0
% E
% Phe:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
0
8
0
0
0
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
8
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
8
0
8
0
8
8
% I
% Lys:
8
0
16
8
16
16
8
0
8
0
0
8
24
0
0
% K
% Leu:
0
16
8
0
8
24
0
0
16
47
16
16
16
0
0
% L
% Met:
16
8
8
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
8
8
0
0
0
0
0
8
0
% N
% Pro:
8
16
16
24
8
0
0
8
0
0
8
0
0
0
0
% P
% Gln:
8
31
0
0
24
8
0
8
16
8
0
24
8
8
8
% Q
% Arg:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
24
8
8
8
24
0
24
16
16
8
16
16
0
24
24
% S
% Thr:
0
0
0
8
8
0
8
8
0
8
8
16
0
0
8
% T
% Val:
0
0
8
0
0
8
0
16
8
8
8
0
0
31
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _