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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
22.73
Human Site:
S577
Identified Species:
41.67
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
S577
H
D
L
K
I
Y
A
S
D
E
G
R
V
Q
M
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
S577
H
D
L
K
I
Y
A
S
D
E
G
R
V
Q
M
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
K428
K
L
K
L
K
K
P
K
Q
L
Q
E
V
L
D
Dog
Lupus familis
XP_535450
1457
162086
S577
H
D
L
K
I
Y
A
S
D
E
G
R
V
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
S577
H
D
L
K
I
Y
A
S
D
E
G
R
V
Q
M
Rat
Rattus norvegicus
P0C644
1434
159600
S579
H
D
L
K
I
Y
A
S
D
E
G
R
V
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
F470
M
E
V
R
H
Q
K
F
F
D
L
F
E
K
C
Chicken
Gallus gallus
XP_413955
1359
152194
E536
P
A
G
R
V
Q
A
E
E
L
G
R
A
F
R
Frog
Xenopus laevis
Q5XHF8
1131
128702
K316
W
K
V
C
L
A
F
K
Q
T
V
C
G
F
D
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
V533
E
L
T
P
A
G
R
V
Q
A
E
E
L
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
S594
H
D
L
K
I
Y
A
S
D
E
G
R
V
Q
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
A508
E
L
R
R
E
G
P
A
L
L
L
I
L
K
W
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
C517
E
L
G
R
A
F
R
C
I
Y
P
G
G
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
0
20
0
0
N.A.
100
N.A.
0
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
33.3
40
13.3
6.6
N.A.
100
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
16
8
54
8
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
8
% C
% Asp:
0
47
0
0
0
0
0
0
47
8
0
0
0
0
16
% D
% Glu:
24
8
0
0
8
0
0
8
8
47
8
16
8
0
0
% E
% Phe:
0
0
0
0
0
8
8
8
8
0
0
8
0
16
0
% F
% Gly:
0
0
16
0
0
16
0
0
0
0
54
8
16
8
8
% G
% His:
47
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
47
0
0
0
8
0
0
8
0
0
0
% I
% Lys:
8
8
8
47
8
8
8
16
0
0
0
0
0
16
0
% K
% Leu:
0
31
47
8
8
0
0
0
8
24
16
0
16
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
47
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
8
0
0
16
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
16
0
0
24
0
8
0
0
54
0
% Q
% Arg:
0
0
8
31
0
0
16
0
0
0
0
54
0
0
16
% R
% Ser:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
0
16
0
8
0
0
8
0
0
8
0
54
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
47
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _