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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
18.18
Human Site:
S698
Identified Species:
33.33
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
S698
E
R
M
Q
D
P
R
S
V
D
L
Q
L
Y
H
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
T686
F
A
L
I
E
N
L
T
H
Q
I
R
E
R
M
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
Y534
G
R
A
F
R
C
M
Y
P
G
G
Q
G
D
Y
Dog
Lupus familis
XP_535450
1457
162086
S698
E
R
M
Q
D
P
K
S
V
D
L
Q
L
Y
H
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
S698
E
R
M
Q
D
P
S
S
V
D
L
Q
L
Y
H
Rat
Rattus norvegicus
P0C644
1434
159600
S700
E
R
M
Q
D
P
S
S
V
D
L
Q
L
Y
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
G576
L
L
V
L
K
W
G
G
E
L
T
P
A
G
R
Chicken
Gallus gallus
XP_413955
1359
152194
E647
Q
K
D
A
E
F
C
E
E
D
Y
E
K
L
A
Frog
Xenopus laevis
Q5XHF8
1131
128702
F422
E
V
R
H
Q
R
F
F
D
L
F
E
K
Y
H
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
M639
K
A
R
L
H
E
I
M
Q
K
D
K
V
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
T714
I
K
K
D
D
P
K
T
K
D
A
I
L
Y
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
L614
S
A
N
T
D
G
L
L
D
D
D
C
Q
A
R
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
E624
F
G
P
R
D
F
N
E
L
A
P
T
G
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
0
13.3
93.3
N.A.
93.3
93.3
N.A.
0
6.6
20
0
N.A.
40
N.A.
13.3
6.6
P-Site Similarity:
100
33.3
20
100
N.A.
93.3
93.3
N.A.
6.6
33.3
26.6
26.6
N.A.
60
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
8
8
0
0
0
0
0
8
8
0
8
8
8
% A
% Cys:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
8
54
0
0
0
16
54
16
0
0
8
0
% D
% Glu:
39
0
0
0
16
8
0
16
16
0
0
16
8
0
0
% E
% Phe:
16
0
0
8
0
16
8
8
0
0
8
0
0
8
0
% F
% Gly:
8
8
0
0
0
8
8
8
0
8
8
0
16
8
0
% G
% His:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
47
% H
% Ile:
8
0
0
8
0
0
8
0
0
0
8
8
0
0
0
% I
% Lys:
8
16
8
0
8
0
16
0
8
8
0
8
16
0
8
% K
% Leu:
8
8
8
16
0
0
16
8
8
16
31
0
39
8
0
% L
% Met:
0
0
31
0
0
0
8
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
39
0
0
8
0
8
8
0
0
0
% P
% Gln:
8
0
0
31
8
0
0
0
8
8
0
39
8
0
0
% Q
% Arg:
0
39
16
8
8
8
8
0
0
0
0
8
0
8
16
% R
% Ser:
8
0
0
0
0
0
16
31
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
8
0
0
0
16
0
0
8
8
0
0
8
% T
% Val:
0
8
8
0
0
0
0
0
31
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
8
0
0
47
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _